Results 111 to 120 of about 1,445 (260)
Abstract Recent advances in AI enable the automatic generation of visualizations directly from textual prompts using agentic workflows. However, visualizations produced via one‐shot generative methods often suffer from insufficient quality, typically requiring a human in the loop to refine the outputs.
Roxana Bujack +4 more
wiley +1 more source
Aim To evaluate whether the General Movement Assessment (GMA) in infancy is associated with later cognitive outcomes from early childhood through adulthood. Method Cohort and case–control studies examining associations between Prechtl's GMA and cognitive outcomes from 6 months of age were eligible.
Sarah E. Hall +11 more
wiley +1 more source
The Chromatic Spectrum of a Ramsey Mixed Hypergraph [PDF]
We extend known structural theorems, primarily a result of Axenovich and Iverson, for the strict edge colorings of the complete graph $K_n$ which avoid monochromatic and rainbow triangles to discover recursive relationships between the chromatic spectra
David Slutzky, Vitaly Voloshin
doaj
Mechanistic insights into HapC: A key enzyme in prodiginine biosynthesis in Hahella chejuensis
HapC catalyzes prodiginine biosynthesis through coordinated movements of its ATP‐binding, substrate‐binding, and catalytic‐swivel domains. The enzyme shows tolerance toward short‐chain MAP analogs, and docking analyses reveal key residues and structural features underlying its substrate flexibility.
Yueh‐Te Chan +10 more
wiley +1 more source
Spatially resolved mapping of histones reveals selective neuronal response in Rett syndrome
Loss of Mecp2 function is associated with Rett syndrome (RTT). MeCP2 regulates chromatin, yet its influence on histone composition and dynamics is unclear. Combining MALDI‐MSI with LCM–LC–MS/MS, we mapped histone proteoforms across the dentate gyrus, cornu ammonis, and cerebellum in two mouse models of RTT.
Frederike Schäfer +6 more
wiley +1 more source
Evolutionary and mechanistic divergence in the Hsp70–Hsp110 chaperone system. Prokaryotic Hsp70s probably diversified into multiple orthologues that cooperated with co‐chaperones such as JDPs and NEF, forming increasingly complex proteostasis networks.
Pierre Goloubinoff +2 more
wiley +1 more source
The genes PH0137, PH0138, and PH0140 form a cluster in the genome of Pyrococcus horikoshii. The PH0140 gene encodes a transcription factor identified as a d‐amino acid‐responsive regulatory protein (DARP). In feast mode, l‐Ile‐bound DARP binds to the promoter and represses transcription of PH0137 and PH0138. In famine mode, DARP binds to d‐allo‐Ile and
Ryushi Kawakami +6 more
wiley +1 more source
PEG400 regulates Falcipain 2 activity through an allosteric mechanism
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath +2 more
wiley +1 more source
Caffeic acid is a central metabolite in the fungal bioluminescence pathway. We identified and characterized caffeylpyruvate hydrolase from Neonothopanus gardneri (ngarCPH) and demonstrate its ability to hydrolyze fungal oxyluciferin into caffeic and pyruvic acids, confirming a complete and self‐sustained fungal bioluminescence cycle.
Caio K. Zamuner +8 more
wiley +1 more source
Rainbow-Colored Carbon Nanotubes via Rational Surface Engineering for Smart Visualized Sensors. [PDF]
Zhang J +11 more
europepmc +1 more source

