Results 111 to 120 of about 1,445 (260)

The Truth, the Whole Truth, and Nothing but the Truth: Automatic Visualization Evaluation from Reconstruction Quality

open access: yesComputer Graphics Forum, EarlyView.
Abstract Recent advances in AI enable the automatic generation of visualizations directly from textual prompts using agentic workflows. However, visualizations produced via one‐shot generative methods often suffer from insufficient quality, typically requiring a human in the loop to refine the outputs.
Roxana Bujack   +4 more
wiley   +1 more source

General Movement Assessment in infancy and later cognitive outcomes: A systematic review and meta‐analysis

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Aim To evaluate whether the General Movement Assessment (GMA) in infancy is associated with later cognitive outcomes from early childhood through adulthood. Method Cohort and case–control studies examining associations between Prechtl's GMA and cognitive outcomes from 6 months of age were eligible.
Sarah E. Hall   +11 more
wiley   +1 more source

The Chromatic Spectrum of a Ramsey Mixed Hypergraph [PDF]

open access: yesComputer Science Journal of Moldova, 2016
We extend known structural theorems, primarily a result of Axenovich and Iverson, for the strict edge colorings of the complete graph $K_n$ which avoid monochromatic and rainbow triangles to discover recursive relationships between the chromatic spectra
David Slutzky, Vitaly Voloshin
doaj  

Mechanistic insights into HapC: A key enzyme in prodiginine biosynthesis in Hahella chejuensis

open access: yesThe FEBS Journal, EarlyView.
HapC catalyzes prodiginine biosynthesis through coordinated movements of its ATP‐binding, substrate‐binding, and catalytic‐swivel domains. The enzyme shows tolerance toward short‐chain MAP analogs, and docking analyses reveal key residues and structural features underlying its substrate flexibility.
Yueh‐Te Chan   +10 more
wiley   +1 more source

Spatially resolved mapping of histones reveals selective neuronal response in Rett syndrome

open access: yesThe FEBS Journal, EarlyView.
Loss of Mecp2 function is associated with Rett syndrome (RTT). MeCP2 regulates chromatin, yet its influence on histone composition and dynamics is unclear. Combining MALDI‐MSI with LCM–LC–MS/MS, we mapped histone proteoforms across the dentate gyrus, cornu ammonis, and cerebellum in two mouse models of RTT.
Frederike Schäfer   +6 more
wiley   +1 more source

Hsp70 diversification and repurposing across the tree of life: Lessons from the evolutionary and mechanistic trajectory of the Hsp70–Hsp110 chaperone system

open access: yesThe FEBS Journal, EarlyView.
Evolutionary and mechanistic divergence in the Hsp70–Hsp110 chaperone system. Prokaryotic Hsp70s probably diversified into multiple orthologues that cooperated with co‐chaperones such as JDPs and NEF, forming increasingly complex proteostasis networks.
Pierre Goloubinoff   +2 more
wiley   +1 more source

A distinct gene expression mechanism for d‐amino acid utilization in hyperthermophilic archaeon Pyrococcus horikoshii

open access: yesThe FEBS Journal, EarlyView.
The genes PH0137, PH0138, and PH0140 form a cluster in the genome of Pyrococcus horikoshii. The PH0140 gene encodes a transcription factor identified as a d‐amino acid‐responsive regulatory protein (DARP). In feast mode, l‐Ile‐bound DARP binds to the promoter and represses transcription of PH0137 and PH0138. In famine mode, DARP binds to d‐allo‐Ile and
Ryushi Kawakami   +6 more
wiley   +1 more source

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

open access: yesThe FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath   +2 more
wiley   +1 more source

Caffeylpyruvate hydrolase from the bioluminescent fungus Neonothopanus gardneri is the key recycling enzyme in the fungal bioluminescence pathway

open access: yesThe FEBS Journal, EarlyView.
Caffeic acid is a central metabolite in the fungal bioluminescence pathway. We identified and characterized caffeylpyruvate hydrolase from Neonothopanus gardneri (ngarCPH) and demonstrate its ability to hydrolyze fungal oxyluciferin into caffeic and pyruvic acids, confirming a complete and self‐sustained fungal bioluminescence cycle.
Caio K. Zamuner   +8 more
wiley   +1 more source

Rainbow-Colored Carbon Nanotubes via Rational Surface Engineering for Smart Visualized Sensors. [PDF]

open access: yesAdv Sci (Weinh), 2023
Zhang J   +11 more
europepmc   +1 more source

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