Results 231 to 240 of about 101,755 (296)

Simple life, simple minds? How habitat simplification in aquatic ecosystems shape fish cognition. [PDF]

Anim Cogn
Klinke A, Brown C.
europepmc   +1 more source

Human FASTK preferentially binds single‐stranded and G‐rich RNA

The FEBS Journal, Volume 293, Issue 3, Page 729-748, February 2026.
Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak, Dawid A. Dzadz, Mikołaj I. Kuska, Madhuri Kanavalli, Maria M. Klimecka, Matthew Merski, Katarzyna J. Bandyra, Maria W. Górna   +7 more
wiley   +1 more source

Cyst-independent oocyte phagocytosis builds the female reproductive reserve in mice. [PDF]

EMBO Rep
Zhang Y, Bo Y, Cheng K, Wang G, Mu L, Liang J, Li L, Geng K, Yang X, Hu X, Wang W, Jia L, Xu X, Hu J, Wang C, Wang F, Ke Y, Xia G, Zhang H.   +18 more
europepmc   +1 more source

CLEC18A interacts with sulfated glycosaminoglycans and controls clear cell renal cell carcinoma progression

The FEBS Journal, Volume 293, Issue 3, Page 709-728, February 2026.
CLEC18A is a previously poorly characterized C‐type lectin. We mapped the expression of CLEC18A to the proximal tubule of the kidney and found CLEC18A to interact with sulfated glycosaminoglycans on proteoglycans. Furthermore, we found that CLEC18A plays an important role in hindering the progression of clear cell renal cell carcinomas in humans and in
Gustav Jonsson, Maura Hofmann, Stefan Mereiter, Lauren Hartley‐Tassell, Masahiro Onji, Irma Sakic, Tiago Oliveira, David Hoffmann, Maria Novatchkova, Alexander Schleiffer, Josef M. Penninger   +10 more
wiley   +1 more source

High genus surface parameterization using the Euclidean Ricci flow method. [PDF]

Sci Rep
Wang YG.
europepmc   +1 more source

Modifying inhibitor specificity for homologous enzymes by machine learning

The FEBS Journal, Volume 293, Issue 4, Page 1007-1023, February 2026.
We present a machine learning method for the design of selective enzyme inhibitors, reducing experimental effort thus accelerating the development of targeted therapeutics. Trained on existing data for three related matrix metalloproteinases (MMPs), our method successfully designed a novel inhibitor variant with enhanced selectivity for one MMP over ...
Dor S. Gozlan, Reut Meiri, Gili Shapira, Matt Coban, Evette S. Radisky, Yaron Orenstein, Niv Papo   +6 more
wiley   +1 more source

Reciprocal frame design for large-scale timber construction. [PDF]

Nat Commun
Xu P, Zhao P, Xia B, Zhao Z, Liu N, Zhang S, Du J.   +6 more
europepmc   +1 more source

A short peptide derived from late embryogenesis abundant proteins enhances acid tolerance in Escherichia coli via modulation of two‐component regulatory systems

The FEBS Journal, Volume 293, Issue 3, Page 781-805, February 2026.
Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley   +1 more source

An In-Depth Statistical Analysis of the TARC Parameter to Evaluate the Real Impact of Random Phases in MIMO Antennas. [PDF]

Sensors (Basel)
Perez-Miguel A, Jardon-Aguilar H, Tirado-Mendez JA, Gomez-Villanueva R, Flores-Leal R, Fritz-Andrade E.   +5 more
europepmc   +1 more source

Phylogenetic reconciliation provides new insights into the evolutionary diversification of the glutamine synthetase gene family in seed plants

The FEBS Journal, Volume 293, Issue 3, Page 859-877, February 2026.
Phylogenetic analyses of glutamine synthetase (GS) in seed plants revealed that all three major evolutionary lineages (GS2, GS1a, and GS1b) must have been present in the common ancestor, with GS2 being the first lineage to diverge. Unlike GS1b, GS1a and GS2 are usually single‐copy genes, even though they underwent duplications that resulted in ...
Elena Aledo, Rafael Antonio Cañas, Francisco R. Cantón, Juan Carlos Aledo   +3 more
wiley   +1 more source