Results 131 to 140 of about 13,107 (297)

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

open access: yesAdvanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu   +5 more
wiley   +1 more source

Mediatized Populisms| New Media, New Partisanship: Divided Virtual Politics In and Beyond Thailand

open access: yesInternational Journal of Communication, 2017
Since the military coup of September 19, 2006, Thailand has been characterized by deeply divided politics. This article examines the rise of partisan television channels closely associated with mass protest movements: ASTV, Asia Update, and Blue Sky ...
Duncan McCargo
doaj  

Lactate Signal: Modulator of Cellular Energy Production and Anabolism

open access: yesAdvanced Science, EarlyView.
Compartmentalized lactate signaling provides a spatial framework for understanding how lactate‐rich states are generated, transported, sensed, and translated into biological outputs. This Review integrates extracellular, cytosolic, mitochondrial‐associated, and nuclear lactate mechanisms to explain how lactate shapes metabolic adaptation, immune ...
Han Wang, Si‐Yuan Yang, Wei Xu
wiley   +1 more source

Trump/Pence Regime Must Go! and Stand Up To Trump, Fight White Supremacy rallies: Protester wearing quilted anti-war coat, Seattle, Washington, November 4, 2017

open access: yes, 2017
Text on clothing reads: "NO WAR". The jacket also has writing in arabic and hebrew, as well as flags of Pakistan, Yemen, Jordan, Afghanistan, Syria, Kuridstan, and Israel.
Kinsey, Kristin
core  

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

open access: yesAdvanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang   +12 more
wiley   +1 more source

Candidate believability at political rallies

open access: yes
Many of our daily encounters with peers, colleagues, friends, and family are communicative settings where our audience consists of more than one person, however, most work within linguistics tends to focus on dyadic interactions. Furthermore, research on
Henriette Johansen
core   +1 more source

Nuciferine Suppresses Inflammatory Hepatocarcinogenesis by Targeting cPLA2‐Dependent Arachidonic Acid Metabolism

open access: yesAdvanced Science, EarlyView.
Nuciferine directly binds the C2 domain of cPLA2, impairing its Ca2+‐dependent membrane translocation and activation. By suppressing arachidonic acid release and downstream pro‐inflammatory eicosanoid production, nuciferine attenuates NF‐κB signaling and inflammatory hepatocarcinogenesis, revealing cPLA2 as a direct molecular target underlying its ...
Jing Sun   +12 more
wiley   +1 more source

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