Results 161 to 170 of about 4,434,687 (184)
Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesis. [PDF]
Journal of Cell Biology, 1993 Ran/TC4, first identified as a well-conserved gene distantly related to H-RAS, encodes a protein which has recently been shown in yeast and mammalian systems to interact with RCC1, a protein whose function is required for the normal coupling of the completion of DNA synthesis and the initiation of mitosis.
Peter D'Eustachio, M G Rush, M Ren
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Small GTP-binding protein Ran is regulated by posttranslational lysine acetylation [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2015 Significance The small GTPase Ran plays fundamental roles in cellular processes such as nucleo-cytoplasmic transport, mitotic spindle formation, and nuclear envelope assembly. Recently, Ran was found to be lysine acetylated, among others, in functionally important regions such as switch I and switch II.
Marcus Krüger +2 more
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The GTP-binding protein Ran/TC4 is required for protein import into the nucleus
Nature, 1993Two cytosolic fractions (A and B) from Xenopus oocytes are sufficient to support protein import into the nuclei of digitonin-permeabilized cells. Fraction A recognizes the nuclear localization sequence (NLS) and binds the import substrate to the nuclear envelope, whereas fraction B mediates the subsequent passage of the bound substrate into the nucleus.
Günter Blobel, Mary Shannon Moore
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Interaction of the Nuclear GTP-Binding Protein Ran with Its Regulatory Proteins RCC1 and RanGAP1
Biochemistry, 1995The guanine nucleotide dissociation and GTPase reactions of Ran, a Ras-related nuclear protein, have been investigated using different fluorescence techniques to determine how these reactions are stimulated by the guanine nucleotide exchange factor RCC1 and the other regulatory protein, RanGAP1 (GTPase-activating protein).
C Klebe, F R Bischoff, Herwig Ponstingl
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Sequence of a canine cDNA clone encoding a Ran/TC4 GTP-binding protein
Gene, 1992We report the isolation and characterization of a canine cDNA encoding a 216-amino acid GTP-binding protein of the Ras superfamily. The protein is almost identical to the human TC4 [Drivas et al., Mol. Cell. Biol. 10 (1990) 1793-1798] and Ran [Bischoff and Ponstingl, Proc. Natl. Acad. Sci.
Vesa M Olkkonen +2 more
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Molecular cloning and DNA sequence of a Dictyostelium cDNA encoding a Ran/TC4 related GTP binding protein belonging to the ras superfamily. [PDF]
Nucleic Acids Research, 1993 John Bush, James Cardelli
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Sequence of a plant cDNA from Vicia faba encoding a novel Ran-related GTP-binding protein
Plant Molecular Biology, 1994A clone obtained from a broad bean (Vicia faba) developing cotyledon cDNA library contained the complete coding sequence of a polypeptide with very high homology to the small GTP-binding proteins Ran from human cells and Spi1 from yeast. These proteins belong to the ras superfamily of proteins involved in different basic cellular processes.
Gerhard Saalbach
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Biochemical and Biophysical Research Communications, 1994
In our effort to identify and study proteins that are important for the progression of the malaria parasite, Plasmodium falciparum, through the cell cycle, we have cloned and sequenced the homologue of Ras-related nuclear protein Ran/TC4 (PfRan). The predicted peptide sequence of PfRan is 214 amino acids long and contains consensus motifs of the Ras ...
F F, Dontfraid, D, Chakrabarti
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In our effort to identify and study proteins that are important for the progression of the malaria parasite, Plasmodium falciparum, through the cell cycle, we have cloned and sequenced the homologue of Ras-related nuclear protein Ran/TC4 (PfRan). The predicted peptide sequence of PfRan is 214 amino acids long and contains consensus motifs of the Ras ...
F F, Dontfraid, D, Chakrabarti
openaire +2 more sources
Acta Physiologiae Plantarum, 2014
Lepidium latifolium L., a weed distributed in the Ladakh region of Himalayan range, belongs to Brassicaceae family and reported to withstand low temperature stress
Vimlendu Bhushan Sinha +2 more
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Lepidium latifolium L., a weed distributed in the Ladakh region of Himalayan range, belongs to Brassicaceae family and reported to withstand low temperature stress
Vimlendu Bhushan Sinha +2 more
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Molecular Reproduction and Development, 2002
AbstractRan, a Ras‐related GTPase, is required for transporting proteins in and out of the nucleus during interphase and for regulating the assembly of microtubules. cDNA cloning shows that rat testis, like mouse testis, expresses both somatic and testis‐specific forms of Ran–GTPase.
Abraham L, Kierszenbaum +3 more
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AbstractRan, a Ras‐related GTPase, is required for transporting proteins in and out of the nucleus during interphase and for regulating the assembly of microtubules. cDNA cloning shows that rat testis, like mouse testis, expresses both somatic and testis‐specific forms of Ran–GTPase.
Abraham L, Kierszenbaum +3 more
openaire +2 more sources