Results 51 to 60 of about 30,184 (259)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Following the Journey of Network Slicing in 5G and 5G Advanced: Essential Concepts, Key Operations, Lifecycle Management, and Future Enhancements

open access: yesIEEE Access
5G networks deliver services with faster speeds, higher capacity, lower latency and higher resilience. Network Slicing is one of the fundamental pillars for offering diverse services.
Rahul Varma Chintalapati   +2 more
doaj   +1 more source

GAN-powered Deep Distributional Reinforcement Learning for Resource Management in Network Slicing

open access: yes, 2019
Network slicing is a key technology in 5G communications system. Its purpose is to dynamically and efficiently allocate resources for diversified services with distinct requirements over a common underlying physical infrastructure.
Chen, Xianfu   +4 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim   +3 more
wiley   +1 more source

Resource Allocation for Network Slicing in RAN Using Case-Based Reasoning

open access: yesApplied Sciences, 2022
As a key technology of 5G, network slicing can meet the diverse needs of users. In this research, we study network slicing resource allocation in radio access networks (RAN) by case-based reasoning (CBR). We treat the user distribution scenario as a case
Dandan Yan, Xu Yang, Laurie Cuthbert
doaj   +1 more source

Maximizing resource utilization by slicing of superscalar architecture

open access: yes, 2006
Superscalar architectural techniques increase instruction throughput from one instruction per cycle to more than one instruction per cycle. Modern processors make use of several processing resources to achieve this kind of throughput.
Patil, Shruti Ravikant
core   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas   +39 more
wiley   +1 more source

Applications of Machine Learning in Resource Management for RAN-Slicing in 5G and Beyond Networks: A Survey

open access: yesIEEE Access, 2022
One of the key foundations of 5th Generation (5G) and beyond 5G (B5G) networks is network slicing, in which the network is partitioned into several separated logical networks, taking into account the requirements of diverse applications. In this context,
Yaser Azimi   +3 more
doaj   +1 more source

Deep Reinforcement Learning for Resource Management in Network Slicing

open access: yes, 2018
Network slicing is born as an emerging business to operators, by allowing them to sell the customized slices to various tenants at different prices. In order to provide better-performing and cost-efficient services, network slicing involves challenging ...
Chen, Xianfu   +7 more
core   +1 more source

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