Results 81 to 90 of about 1,506,345 (248)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Quantum advantages in random access codes
A random access code (RAC), corresponding to a communication primitive with various applications in quantum information theory, is an instance of a preparation-and-measurement scenario.
Andris Ambainis +4 more
doaj +1 more source
An access scheme based on the random access occasion dynamic allocation
With the rapid development of the internet of things (IoT), the application of machine type communication (MTC) in life has grown substantially, and the deployment of machine type devices (MTD) has become more and more intensive.In this case, if there is
Shaoxiong JING +3 more
doaj
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Satellite Internet of Things (IoT) terminals face design constraints regarding low power consumption and light control. These constraints pose a significant collision risk when utilizing traditional random-access protocols, making it challenging to meet ...
Xinjie Zhao +6 more
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Random Access Remixing On The Ipad
Remixing audio samples is a common technique for the creation of electronic music, and there are a wide variety oftools available to edit, process, and recombine pre-recordedaudio into new compositions. However, all of these toolsconceive of the timeline of the pre-recorded audio and theplayback timeline as identical.
Jon Forsyth +2 more
openaire +2 more sources
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

