Results 171 to 180 of about 2,490,701 (287)

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source

Bit Allocation in Spatially Correlated Sensor Fields: A Comparative Study of Contribution-Aware and Heuristic Approaches. [PDF]

Sensors (Basel)
Byun SS.
europepmc   +1 more source

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Joint Access Authentication and Task Collaboration for Dynamic Cross-Domain Resource Management in Satellite Networks. [PDF]

Sensors (Basel)
Zhu J, Zhang N, Yang Y, Yao Y, Qi W, Wang Y.   +5 more
europepmc   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

Advanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon, Seo‐Hyeon Bae, Jungyong Ji, Jisun Lee, Hosam Choi, Min‐Ho Kang, Sang‐In Park, Hyemin Kim, Nakyung Lee, Hajin Lee, Seonghoon Kim, Jungmin Kim, Subin Yoon, Seonghyun Lee, Seongje Cho, Dahyeon Ha, Ayoung Oh, Sohee Jo, Huijeong Choi, Yeeun Lee, Sowon Lee, Hyo‐Jung Park, Gitak Nam, Jisu Shin, Yujin Kang, Wonpil Im, Kiyoun Lee, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Estimation of Underlying Normal Distribution Parameters From Dichotomized Data. [PDF]

Biom J
Liu Z, Shang L, Lesperance M, Zhou S, Zhang X.   +4 more
europepmc   +1 more source

Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants

Advanced Science, EarlyView.
A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr, Reuben Rideaux, Amaya J. Fox, David R. Lightfoot, Jason Tangen, Jason B. Mattingley, Shane E. Ehrhardt   +6 more
wiley   +1 more source

Does randomization matter in rare disease clinical trials. [PDF]

PLoS One
Wied S, Razsolkov DK, Heussen N, Hilgers RD.   +3 more
europepmc   +1 more source

Space‐Time Metasurface Antenna Enabled High‐Dimensional Electromagnetic Modulation for Intrinsic Physical Layer Security

Advanced Science, EarlyView.
The concept of high‐dimensional EM modulation using the STMA for physical layer secure communication is illustrated in figure. The STMA consists of a series of programmable unit cells, with 1‐bit reconfigurable phase states (0/π). The STMA is excited by a monochromatic continuous wave (CW) at frequency fc and controlled by a field‐programmable gate ...
Xinyu Fang, Yiqing Sun, Chenfeng Yang, Siran Wang, Zheng Xing Wang, Kaixu Wang, Geng‐Bo Wu   +6 more
wiley   +1 more source

Artificial intelligence and machine learning in heart and lung transplantation. [PDF]

EClinicalMedicine
Sharma G, Kamal VK, Truby LK, Farr M, Timofte I, Kaza V, Lesaja S, Murala JSK, Keshavamurthy S, Peltz M, Jessen ME.   +10 more
europepmc   +1 more source