Results 101 to 110 of about 6,616 (301)
Regularity of random attractors for stochastic semilinear degenerate parabolic equations
Electronic Journal of Differential Equations, 2012 We consider the stochastic semilinear degenerate parabolic equation $$ du+[- operatorname{div}(sigma(x)abla u) + f(u) + lambda u]dt = gdt+ sum_{j=1}^{m}h_j{domega_j} $$ in a bounded domain $mathcal{O}subset mathbb {R}^N$, with the nonlinearity ...
Cung The Anh +2 more
doaj
A Novel Method for Designing Multistable Systems with a Hidden Attractor
AxiomsDynamical systems with chaotic attractors are an interesting topic not only for their complex behavior but also due to their potential applications. Along with the chaos, systems can also present interesting features such as multistability, global basin ...
Rodolfo de Jesús Escalante-González +2 more
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Asymptotic behavior for non-autonomous stochastic plate equation on unbounded domains
Open Mathematics, 2019 We study the asymptotic behavior of solutions to the non-autonomous stochastic plate equation driven by additive noise defined on unbounded domains.
Yao Xiaobin, Liu Xilan
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Random attractors for quasi-continuous random dynamical systems and applications to stochastic reaction–diffusion equations [PDF]
, 2008 This paper first introduces the so-called quasi-continuous random dynamical system (RDS) on a separable Banach space. The quasi-continuity is weaker than all the usual continuities and thus is easier to check in practice.
Li, Yangrong, Guo, Boling
core +1 more source
Estimating Attractor Reachability in Asynchronous Logical Models
Frontiers in Physiology, 2018 Logical models are well-suited to capture salient dynamical properties of regulatory networks. For networks controlling cell fate decisions, cell fates are associated with model attractors (stable states or cyclic attractors) whose identification and ...
Nuno D. Mendes +7 more
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source