Results 171 to 180 of about 841,294 (188)

HyperDeepTAD: a topologically associated domains detection method based on multiway chromatin interaction data and deep learning. [PDF]

BMC Genomics
Luo J, Liu K, Feng R, Guo F.
europepmc   +1 more source

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, EarlyView.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source

MedZeroSeg: Zero-shot medical image segmentation via vision foundation models. [PDF]

PLoS One
Zhang R, Huang M, Li R.
europepmc   +1 more source

Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming

Advanced Materials, EarlyView.
Matrix viscoelasticity is a key mechanical feature of the tumor microenvironment but remains poorly understood in immune regulation. Here, we develop a tunable collagen platform to decouple viscoelasticity from stiffness and show that slow‐relaxing matrices constrain dendritic cell migration by limiting actomyosin‐driven matrix remodeling, thereby ...
Wei‐Hung Jung, Emie Humann, Joshua M. Price, Yoav Binenbaum, Azra Haseki, Sanjana Iyer, David J. Mooney   +6 more
wiley   +1 more source

Landscape-socioeconomic feedback mechanisms in Sichuan's river basins. [PDF]

iScience
Shen R, Shu S, Wang Y, Tian Y, Chen W.
europepmc   +1 more source

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

Dynamic involvement of the core gut microbiome XNP_Guild1 in the evolution of gestational diabetes mellitus. [PDF]

Gut Microbes
Du H, Lin Q, He X, Yang B, Huang Y, Li Q, Wang Y, Wen R, Lin W, Li S, Zheng L, Ou Z.   +11 more
europepmc   +1 more source

Evolution and structural resilience assessment of the frozen meat trade network. [PDF]

PLoS One
Zhang M, Li Y, Huang X, Fu Y, Tian W.
europepmc   +1 more source

Influence of Architected Core Topology on the Dynamic and Flexural Behaviour of Multi-Material Sandwich Structures. [PDF]

Polymers (Basel)
Doğanay Katı H, Khan M.
europepmc   +1 more source

EPOP and MTF2 activate PRC2 activity through DNA-sequence specificity. [PDF]

Proc Natl Acad Sci U S A
Granat J, Liu S, Popoca L, Oksuz O, Reinberg D.   +4 more
europepmc   +1 more source