Results 121 to 130 of about 4,430,595 (297)
Thermal environment and maternal effects shape egg size in a freshwater fish
Ecosphere, 2016 Offspring size determines offspring survival rates; thus, understanding factors influencing offspring size variability could elucidate variation in population dynamics.
Zachary S. Feiner +8 more
doaj +1 more source
Effective random seeding of random number generators [PDF]
Behavior Research Methods & Instrumentation, 1981 To obtain different sequences of values from a random number generating algorithm, we must start with different seed values or discard a variable number of initial samples. For maximum independence among sequences, differences must include the lowest order seed bits, and some generators require one to wait many samples for differences to propagate to ...
openaire +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Energy Transition in the GCC: From Oil Giants to Green Leaders?
EnergiesDuring the 28th Conference of the Parties (COP28), organized under the United Nations Framework Convention on Climate Change and hosted by the United Arab Emirates, member nations reached a global agreement to begin transitioning away from fossil fuel ...
Jihen Bousrih, Manal Elhaj
doaj +1 more source
The Choice between fixed and random effects models: some considerations for educational research. [PDF]
We discuss the use of fixed and random effects models in the context of educational research and set out the assumptions behind the two modelling approaches.
Anna Vignoles +3 more
core
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
, 2014 We illustrate a class of conditional models for the analysis of longitudinal data suffering attrition in random effects models framework, where the subject-specific random effects are assumed to be discrete and to follow a time-dependent latent process ...
Maruotti, Antonello
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source