Results 161 to 170 of about 1,535,509 (313)

Improved prediction and flagging of extreme random effects for non-Gaussian outcomes using weighted methods. [PDF]

Biometrics
Neuhaus J, McCulloch C, Boylan R.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

A two-stage random-effects estimator for meta-analyses of the value per statistical life. [PDF]

PLoS One
Newbold SC, Dockins C, Simon N, Maguire K, Sakib AM.   +4 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Incidence Proportions From Random-Effects Meta-Analyses of Rare Events With Large Cluster Heterogeneity, Including Sensitivity to the Normal Distribution Assumption. [PDF]

Cureus
Dexter F, Sondekoppam R, Bayman EO.
europepmc   +1 more source

A comparison of the effects of midazolam, propofol and dexmedetomidine on the antioxidant system: A randomized trial

, 2015
Chao Han, Weiliang Ding, Wenjie Jiang, Yuhu Chen, DONGYUAN HANG, GU Da-ming, Guojun Jiang, Yongfei Tan, Zhijun Ge, Tieliang Ma   +9 more
openalex   +2 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

DSLE2 random-effects meta-analysis model for high-throughput methylation data. [PDF]

BMC Genomics
Wang N, Zhou Y, Zhu F, Jin S.
europepmc   +1 more source

Tweedie Compound Poisson Models with Covariate-Dependent Random Effects for Multilevel Semicontinuous Data. [PDF]

Entropy (Basel), 2023
Ma R, Islam MD, Hasan MT, Jørgensen B.
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source