Results 71 to 80 of about 4,395,518 (296)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The R Package JMbayes for Fitting Joint Models for Longitudinal and Time-to-Event Data Using MCMC

open access: yesJournal of Statistical Software, 2016
Joint models for longitudinal and time-to-event data constitute an attractive modeling framework that has received a lot of interest in the recent years.
Dimitris Rizopoulos
doaj   +1 more source

Nonparametric inference procedure for percentiles of the random effects distribution in meta-analysis

open access: yes, 2010
To investigate whether treating cancer patients with erythropoiesis-stimulating agents (ESAs) would increase the mortality risk, Bennett et al. [Journal of the American Medical Association 299 (2008) 914--924] conducted a meta-analysis with the data from
Cai, Tianxi   +3 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Empirical Bayes for group (DCM) studies: a reproducibility study

open access: yesFrontiers in Human Neuroscience, 2015
This technical note addresses some key reproducibility issues in the dynamic causal modelling of group studies of event related potentials. Specifically, we address the reproducibility of Bayesian model comparison (and inferences about model parameters ...
Vladimir eLitvak   +3 more
doaj   +1 more source

Estimation in Dirichlet random effects models

open access: yes, 2010
We develop a new Gibbs sampler for a linear mixed model with a Dirichlet process random effect term, which is easily extended to a generalized linear mixed model with a probit link function.
Casella, George   +2 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

International trade and economic growth in Africa: The role of the digital economy

open access: yesCogent Economics & Finance, 2021
This paper examines the role the digital economy plays in international trade impacts on Africa’s economic growth based on 53 countries’ sample from 2000–2018.
Simon Abendin, Pingfang Duan
doaj   +1 more source

Confinement-deconfinement and universal string effects from random percolation

open access: yes, 2003
The 't Hooft criterion leading to confinement out of a percolating cluster of central vortices suggests defining a novel three-dimensional gauge theory directly on a random percolation process.
't Hooft   +7 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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