Results 91 to 100 of about 3,644,468 (346)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Prediction models for clustered data with informative priors for the random effects: a simulation study

BMC Medical Research Methodology, 2018
Background Random effects modelling is routinely used in clustered data, but for prediction models, random effects are commonly substituted with the mean zero after model development.
Haifang Ni, Rolf H. H. Groenwold, Mirjam Nielen, Irene Klugkist   +3 more
doaj   +1 more source

Random effects compound Poisson model to represent data with extra zeros

, 2009
This paper describes a compound Poisson-based random effects structure for modeling zero-inflated data. Data with large proportion of zeros are found in many fields of applied statistics, for example in ecology when trying to model and predict species ...
Etienne, Marie-Pierre, Hugues, Benoit, Jacques, Bernier, Parent, Eric   +3 more
core  

Effects of Random Biquadratic Couplings in a Spin-1 Spin-Glass Model

, 2000
A spin-1 model, appropriated to study the competition between bilinear (J_{ij}S_{i}S_{j}) and biquadratic (K_{ij}S_{i}^{2}S_{j}^{2}) random interactions, both of them with zero mean, is investigated.
da Costa, F. A., de Araujo, J. M., Nobre, F. D.   +2 more
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Fixed and random effects in Classical and Bayesian regression [PDF]

This paper proposes a common and tractable framework for analyzing different definitions of fixed and random effects in a contant-slope variable-intercept model. It is shown that, regardless of whether effects (i) are treated as parameters or as an error
Silvio Rendón
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Integrating Logistics into Global Production: A New Approach

Logistics
Background: Logistics has become a key driver of global economic production. This study investigates the role of logistics in global economic production by presenting a novel theoretical framework that integrates logistics performance into traditional ...
Pablo Coto-Millán, David Paz Saavedra, Marta de la Fuente, Xose Luis Fernandez   +3 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

The Impact of Firms' Carbon Emissions on Financial Performance and the Role of Innovation: Evidence from Türkiye

Mehmet Akif Ersoy Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi
Carbon emissions, one of the main causes of climate change and environmental degradation, have recently become extremely important. In parallel, firms' disclosure of their environmental performance and activities to reduce carbon emissions are viewed ...
Musa Özçelik, Seren Aydıngülü Sakalsız   +1 more
doaj   +1 more source