Results 171 to 180 of about 5,148,982 (304)

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Elements Fall 2021

, 2022
Elements
core  

Convergence of weighted sums of random elements in D[0, 1]

Convergence in probability for Toeplitz weighted sums is obtained for convex tight random elements in D[0, 1] under pointwise conditions. The almost sure convergence of the weighted sums is proved for independent, convex tight random elements and for ...
Taylor, Robert Lee, Daffer, Peter Z.
core  

Non-Random Association of Ultraconserved Genomic Elements (UCE) with Human Genes. [PDF]

Int J Mol Sci
Fedorova L, Orlov YL, Mulyar OA, Fedorov A.   +3 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Optimization Scheme for Hybrid RIS-Assisted ISAC System for Controllable Communication and Sensing. [PDF]

Sensors (Basel)
Deng Z, Li B, Wang H.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Enhanced Generalization through Atomic Embeddings and Cross-Element Parameterization. [PDF]

J Chem Inf Model
Taleblou M, Pellegrini F, de Gironcoli S.   +2 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Stability analysis of landslide dam slopes based on the local strength reduction-random finite element method. [PDF]

PLoS One
Shi N, Zhao X, Huang J, Li H.
europepmc   +1 more source