Advanced Science, EarlyView.This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun +17 more
wiley +1 more source
Artificial intelligence strategies based on random forests for detecting ischemia-reperfusion injury changes in kidney tissue during intravital imaging. [PDF]
Sci RepPantic I +5 more
europepmc +1 more source
Exploring the variable importance in random forests under correlations: a general concept applied to donor organ quality in post-transplant survival. [PDF]
BMC Med Res Methodol, 2023 Wies C +3 more
europepmc +1 more source
The Journal of The Institute of Image Information and Television Engineers, 2012 openaire +2 more sources
Random Forests model selection
, 2016 Random Forests (RF) of tree classifiers are a popular ensemble method for classification. RF have shown to be effective in many different real world classification problems and nowadays are considered as one of the best learning algorithms in this context.
ORLANDI, ILENIA +2 more
openaire +2 more sources
Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors
Advanced Science, EarlyView.Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon +10 more
wiley +1 more source
Simulating Public Opinion: Comparing Distributional and Individual-Level Predictions from LLMs and Random Forests. [PDF]
Entropy (Basel)Miranda F, Balbi PP.
europepmc +1 more source
Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression
Advanced Science, EarlyView.Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo +15 more
wiley +1 more source
Metabolomics and random forests in patients with complex congenital heart disease. [PDF]
Front Cardiovasc Med, 2022 Michel M +4 more
europepmc +1 more source
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
Advanced Science, EarlyView.CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source