Results 91 to 100 of about 8,436,612 (364)

On Structured Random Matrices Defined by Matrix Substitutions

Mathematics, 2023
The structure of the random matrices introduced in this work is given by deterministic matrices—the skeletons of the random matrices—built with an algorithm of matrix substitutions with entries in a finite field of integers modulo some prime number, akin
Manuel L. Esquível, Nadezhda P. Krasii
doaj   +1 more source

Singular random matrix decompositions: Jacobians [PDF]

Journal of Multivariate Analysis, 2005
For a singular random matrix Y, we find the Jacobians associated with the following decompositions; QR, Polar, Singular Value (SVD), L'U, L'DM and modified QR (QDR). Similarly, we find the Jacobinas of the following decompositions: Spectral, Cholesky's, L'DL and symmetric non-negative definite square root, of the cross-product matrix S = Y'Y.
González Farías, Graciela, Díaz García, José A.   +1 more
openaire   +3 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Identifying Functional Modules of Diffuse Large B-cell Lymphoma Gene Co-expression networks by Hierarchical Clustering Method Based on Random Matrix Theory

Nano Biomedicine and Engineering, 2011
In this work, we propose an original method, the Random matrix theory (RMT)-based hierarchical clustering method, to identify functional gene networks of diffuse large B-cell Lymphoma (DLBCL) gene co-expression networks.
Jian Chen, Kaiwang Zhang, Jianxin Zhong
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

From non-ergodic eigenvectors to local resolvent statistics and back: A random matrix perspective [PDF]

, 2016
We study the statistics of the local resolvent and non-ergodic properties of eigenvectors for a generalised Rosenzweig-Porter random matrix model, undergoing two transitions separated by a delocalised non-ergodic phase.
Davide Facoetti, P. Vivo, G. Biroli
semanticscholar   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Random Matrix Theory and Quantum Chromodynamics

, 2016
These notes are based on the lectures delivered at the Les Houches Summer School in July 2015. They are addressed at a mixed audience of physicists and mathematicians with some basic working knowledge of random matrix theory. The first part is devoted to
Akemann, Gernot
core   +1 more source

Multiradar Collaborative Task Scheduling Algorithm Based on Graph Neural Networks with Model Knowledge Embedding

Leida xuebao
Modern radar systems face increasingly complex challenges in tasks such as detection, tracking, and identification. The diversity of task types, limited data resources, and strict execution time requirements make radar task scheduling a strongly NP-hard ...
Haoqing LI, Dian YU, Changchun PAN, Wenxian YU, Dongying LI   +4 more
doaj   +1 more source