Results 81 to 90 of about 8,436,612 (364)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Random access-random release relay switching matrix [PDF]

, 1968
XY relay switching matrix provides complete random access and random release of 400 points. A mercury-wetted bistable relay with independent set and reset coils is the unique feature associated with each ...
Carter, J. A., Evans, F. E.
core   +1 more source

Detection of Abnormal Power Consumption State Based on VMD Decomposition and Random Matrix Theory

Taiyuan Ligong Daxue xuebao
Purposes Users’ abnormal power consumption behaviors need to be distinguished quickly and accurately. Methods An abnormal state detection model is proposed on the basis of smart meter data and data decomposition and random matrix theory, realizing the ...
Zhiqin QIN, Yuhuan HAN, Yi ZHANG, Zhijun GUO, Yingwei XU, Zexuan JIN   +5 more
doaj   +1 more source

Complex Langevin simulation of a random matrix model at nonzero chemical potential [PDF]

, 2017
A bstractIn this paper we test the complex Langevin algorithm for numerical simulations of a random matrix model of QCD with a first order phase transition to a phase of finite baryon density. We observe that a naive implementation of the algorithm leads
J. Bloch, J. Glesaaen, J. Verbaarschot, S. Zafeiropoulos, S. Zafeiropoulos, S. Zafeiropoulos   +5 more
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Non-Equilibrium Random Matrix Theory : Transition Probabilities [PDF]

, 2016
In this letter we present an analytic method for calculating the transition probability between two random Gaussian matrices with given eigenvalue spectra in the context of Dyson Brownian motion.
Pedro, Francisco Gil, Westphal, Alexander   +1 more
core   +3 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Dynamical correlation functions for products of random matrices

, 2015
We introduce and study a family of random processes with a discrete time related to products of random matrices. Such processes are formed by singular values of random matrix products, and the number of factors in a random matrix product plays a role of ...
Strahov, Eugene
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Distributed Tracking of Extended Target With Orientation Using Variational Bayesian

IET Radar, Sonar & Navigation
In this work, we propose an alternative distributed tracking approach for extended target with time‐varying orientation in a sensor network. Within the random matrix framework, we employ a Gaussian prior for the orientation, the inverse Gamma priors for ...
Qinqin Jiao
doaj   +1 more source