Results 61 to 70 of about 129,650 (250)
Hydrodynamic Theory of the Connected Spectral form Factor
One manifestation of quantum chaos is a random-matrix-like fine-grained energy spectrum. Prior to the inverse level spacing time, random matrix theory predicts a “ramp” of increasing variance in the connected part of the spectral form factor. However, in
Michael Winer, Brian Swingle
doaj +1 more source
Raney Distributions and Random Matrix Theory [PDF]
Recent works have shown that the family of probability distributions with moments given by the Fuss-Catalan numbers permit a simple parameterized form for their density. We extend this result to the Raney distribution which by definition has its moments given by a generalization of the Fuss-Catalan numbers.
Forrester, PJ, Liu, D-Z
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This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The geometry of evolved community matrix spectra
Random matrix theory has been applied to food web stability for decades, implying elliptical eigenvalue spectra and that large food webs should be unstable.
Silja Borring Låstad, Jan O. Haerter
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We present a gravitational theory that interpolates between JT gravity, and a gravity theory with a fixed boundary Hamiltonian. For this, we consider a matrix integral with the insertion of a Gaussian with variance $\sigma^2$, centered around a matrix
Andreas Blommaert, Jorrit Kruthoff
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Proof methods in random matrix theory
In this survey article, we give an introduction to two methods of proof in random matrix theory: The method of moments and the Stieltjes transform method. We thoroughly develop these methods and apply them to show both the semicircle law and the Marchenko-Pastur law for random matrices with independent entries.
Fleermann, Michael, Kirsch, Werner
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Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
N $$ \mathcal{N} $$ = 2 JT supergravity and matrix models
Generalizing previous results for N $$ \mathcal{N} $$ = 0 and N $$ \mathcal{N} $$ = 1, we analyze N $$ \mathcal{N} $$ = 2 JT supergravity on asymptotically AdS2 spaces with arbitrary topology and show that this theory of gravity is dual, in a holographic
Gustavo J. Turiaci, Edward Witten
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source

