Seismic slope stability analysis using modified pseudo dynamic method with uniform random field of initial phases. [PDF]
PLoS OneXu L, Jing H, Wen J, Li L, Song Z.
europepmc +1 more source
Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
Advanced Healthcare Materials, EarlyView.This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla +16 more
wiley +1 more source
Recent Perspectives in Random Matrix Theory and Number Theory: Basic analytic number theory [PDF]
, 2005 David W. Farmer
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Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis
Advanced Healthcare Materials, EarlyView.Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim +10 more
wiley +1 more source
Detection and evaluation of clusters within sequential data. [PDF]
Data Min Knowl DiscovVan Werde A +3 more
europepmc +1 more source
Rolling Ultrasharp Microneedle Spheres Enable Topical Delivery of Biologics Through the Skin
Advanced Healthcare Materials, EarlyView.Rolling ultraminiaturized microneedle spheres (RUMS), created via two‐photon polymerization, unlock effective and painless topical delivery of messenger RNA (mRNA) and drugs through the skin. By gently forming thousands of microscopic pores, RUMS boost skin permeability by up to 100‐fold.
Theocharis Nikiforos Iordanidis +6 more
wiley +1 more source
Rain-Induced Vibration Energy Harvesting Using Nonlinear Plates with Piezoelectric Integration and Power Management. [PDF]
Sensors (Basel)Wang YR, Lin WT, Huang BJ.
europepmc +1 more source
Differential Phase Contrast Imaging to Predict MSC Immune Function
Advanced Healthcare Materials, EarlyView.This work employs quantitative differential phase contrast (qDPC) imaging technique to non‐invasively extract morphological features from live Mesenchymal Stromal Cells (MSCs) for single cell prediction on cell immunomodulatory capacity. This work establishes a foundation for scalable, non‐destructive monitoring of MSCs immunomodulatory capacity ...
Kejie Rui +5 more
wiley +1 more source
Reordered hierarchical complexity in ecosystems with delayed interactions. [PDF]
PNAS NexusQin BW +6 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.This study presents alkylated nitrobenzoselenadiazole (NBSD) photosensitizers that self‐assemble into programmable aggregates, enabling photo‐triggered pyroptosis and enhanced ROS generation. The lead compound, NBSD‐NOc, exhibits superior photodynamic activity, high cellular uptake, and implantable gel compatibility with pH‐responsive release.
Jong Min An +8 more
wiley +1 more source