Results 71 to 80 of about 830,257 (263)
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Multifractal Image Analysis of Electrostatic Surface Microdischarges
The multifractal image analysis of Lichtenberg figures has confirrmed a self- similar arrangement of surface streamers belonging to the special case of electrostatic separation discharges propagating along a surface of polymeric dielectrics.
T. Ficker
doaj
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Stochastic performance analysis of a time‐of‐arrival quantum random number generator
The performance analysis of a quantum random number generator (QRNG), operating based on the interarrival time differences between consecutive photon detections from a coherent light source, is presented.
Ágoston Schranz +2 more
doaj +1 more source
A multiplicative wavelet-based model for simulation of a random process
We find a multiplicative wavelet-based representation for stochastic processes that can be represented as the exponent of a second-order centered random process.
Ievgen Turchyn
doaj +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Turbulent Intermittency in a Random Fiber Laser
In fluid turbulence, intermittency is the emergence of non-Gaussian tails in the distribution of velocity increments in small space and/or time scales. Intermittence is thus expected to gradually disappear as one moves from small to large scales. Here we
Antônio M. S. Macêdo +4 more
doaj +1 more source

