Results 121 to 130 of about 4,929,720 (302)

From satellites to the milking parlor: National Aeronautics and Space Administration prediction of worldwide energy resources as an information source for the national genetic evaluation of heat stress tolerance in Holstein and Gir cattle

Journal of Dairy Science
: Heat stress is a major constraint to dairy productivity in tropical regions, where environmental conditions frequently exceed thermoneutral thresholds.
Magno P. Neves, Annaiza B. Bignardi, Amanda B.S. Souza, Rodrigo J. Pereira, Maria G.C.D. Peixoto, Frank A.T. Bruneli, Ricardo G. Andrade, Cláudio N. Costa, Luiz F. Brito, Mário L. Santana   +9 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Novel methods for quantifying individual host response to infectious pathogens for genetic analyses

Frontiers in Genetics, 2012
Here we propose two novel approaches for describing and quantifying the response of individual hosts to pathogen challenge in terms of infection severity and impact on host performance.
Andrea B Doeschl-Wilson, Steve eBishop, Ilias eKyriazakis, Beatriz eVillanueva   +3 more
doaj   +1 more source

Beta-Stacy survival regression models [PDF]

, 2007
This paper introduces a class of survival models for discrete time-to-event data with random right censoring. Flexible distributions for the survival times are constructed by modelling the random survival functions as discrete-time beta-Stacy processes (
Muliere, Pietro, Rigat, Fabio
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Randomization Does Not Justify Logistic Regression

Statistical Science, 2008
Published in at http://dx.doi.org/10.1214/08-STS262 the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http://www.imstat.org)
openaire   +3 more sources

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Random regression models for detection of gene by environment interaction

Genetics Selection Evolution, 2007
Two random regression models, where the effect of a putative QTL was regressed on an environmental gradient, are described. The first model estimates the correlation between intercept and slope of the random regression, while the other model restricts ...
Meuwissen Theo HE, Ødegård Jørgen, Lillehammer Marie   +2 more
doaj   +1 more source

Random-effects parameters for multivariable regression model for the association between body weight and pre-weaning dietary group.

, 2018
Random-effects parameters for multivariable regression model for the association between body weight and pre-weaning dietary group.
C. McGregor Argo (4853509), G. Curtis (4853515), D. Grove-White (4853512), D. Jones (2844365)   +3 more
core   +1 more source