Results 31 to 40 of about 816,699 (265)

EM-REML estimation of covariance parameters in Gaussian mixed models for longitudinal data analysis

open access: yesGenetics Selection Evolution, 2000
This paper presents procedures for implementing the EM algorithm to compute REML estimates of variance covariance components in Gaussian mixed models for longitudinal data analysis.
Robert-Granié Christèle   +2 more
doaj   +1 more source

Stein Random Feature Regression

open access: yesCoRR
In large-scale regression problems, random Fourier features (RFFs) have significantly enhanced the computational scalability and flexibility of Gaussian processes (GPs) by defining kernels through their spectral density, from which a finite set of Monte Carlo samples can be used to form an approximate low-rank GP.
Houston Warren   +2 more
openaire   +3 more sources

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris   +24 more
wiley   +1 more source

The PX-EM algorithm for fast stable fitting of Henderson's mixed model

open access: yesGenetics Selection Evolution, 2000
This paper presents procedures for implementing the PX-EM algorithm of Liu, Rubin and Wu to compute REML estimates of variance covariance components in Henderson's linear mixed models.
Van Dyk David A, Foulley Jean-Louis
doaj   +1 more source

Sociodemographic Factors Associated With Later Stage at Diagnosis of Pediatric Germ Cell Tumors: A Report From Children's Oncology Group Registries ACCRN07 and APEC14B1

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Germ cell tumors (GCTs) often arise in the ovaries and testes (extracranial) but can also develop in the brain (intracranial). We examined the relationship of individual, family, and community‐level socioeconomic status (SES) with stage of disease at diagnosis in a cohort of pediatric patients with GCT from Children's Oncology Group
Heydon K. Kaddas   +7 more
wiley   +1 more source

Phase Angle as an Early Functional Biomarker of Cancer‐Related Fatigue in Pediatric Oncology: A Prospective Longitudinal Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric cancer remains a leading cause of morbidity and mortality worldwide, particularly in low‐and middle‐income countries. Cancer treatment may impair nutritional status, alter body composition, and exacerbate cancer‐related fatigue (CRF).
Luís Carlos Lopes‐Junior   +11 more
wiley   +1 more source

Genetic evaluation of daily gains of dual-purpose bulls using a random regression model

open access: yesCzech Journal of Animal Science, 2008
Daily gains of 8 243 dual-purpose bulls from 100 to 400 days of age during the years 1971 to 2007 were analyzed by random regression models. Orthogonal Legendre polynomials (LP) of degree 4 were applied to daily gains calculated at 30-day intervals over ...
H. Krejčová   +4 more
doaj   +1 more source

Development and Implementation of a Disease‐Targeted Storybook as a Clinical Tool for Children With Acute Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Although significant progress has been made in childhood leukemia survival, healthcare providers, and caregivers often face challenges in explaining this disease to patients. Disease‐targeted storybooks have been proposed as a tool to facilitate the understanding of diagnoses and treatment.
Nutvipha Ummartyotin   +6 more
wiley   +1 more source

Estimates of genetic trends for daily milk yield and somatic cell score of primiparous Holstein cattle in Iran

open access: yesJournal of Applied Animal Research, 2019
Genetic and permanent environmental correlations between milk yield and somatic cell score (SCS) were estimated. The data set used in this analyse contained a total of 204,438 test-day (TD) observations of milk yield and SCS from 22,903 primiparous ...
Khabat Kheirabadi
doaj   +1 more source

Trajectory of body weight of performance tested dual-purpose bulls

open access: yesCzech Journal of Animal Science, 2007
6 508 bulls of dual-purpose cattle at performance-test stations were weighed at intervals of 30 days from birth to 420 days. After all editing a total of 74 558 weight records were available.
J. Přibyl   +5 more
doaj   +1 more source

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