Results 71 to 80 of about 609,661 (311)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Revising and Validating the Random Search Model for Competitive Search [PDF]
, 1998 A random search model was fit to a total of 2592 visual search times on a single-target detection task. By using a competing homogeneous background and uniform stimulus material, specifying viewing distance, controlling the presentation of search task ...
Alan J. Courtney, Alan H. S. Chan
core +1 more source
Greedy Randomized Adaptive Search Procedures [PDF]
Journal of Global Optimization, 1995 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Thomas A. Feo, Mauricio G. C. Resende
openaire +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Four-factor computing experiment for the random walk on a two-dimensional square field [PDF]
Компьютерные исследования и моделирование, 2017 Nowadays the random search became a widespread and effective tool for solving different complex optimization and adaptation problems. In this work, the problem of an average duration of a random search for one object by another is regarded, depending on ...
Olga Vladimirovna Maksimova +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Random search algorithms [PDF]
, 2009 Random search algorithms are useful for many ill-structured global optimization problems with continuous and/or discrete variables. Typically random search algorithms sacrifice a guarantee of optimality for finding a good solution quickly with ...
Zelda B. Zabinsky
core
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Implicit search trails for video recommendation [PDF]
, 2008 In this demo paper we demonstrate our approach and system for using implicit actions involved in video search to provide recommendations to users. The goal of this system is to improve the quality of the results that users find, and in doing so, help ...
Vallet, D. +3 more
core
Hyperparameter space for random search. [PDF]
, 2020 Hyperparameter space for random search.
Yoshihide Sekimoto (499186) +4 more
core +1 more source