Results 131 to 140 of about 609,661 (311)

Stochastic Optimization with Random Search

CoRR
We revisit random search for stochastic optimization, where only noisy function evaluations are available. We show that the method works under weaker smoothness assumptions than previously considered, and that stronger assumptions enable improved guarantees. In the finite-sum setting, we design a variance-reduced variant that leverages multiple samples
El Mahdi Chayti, Taha el Bakkali el Kadi, Omar Saadi, Martin Jaggi   +3 more
openaire   +2 more sources

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Ordered Search in Differentiated Markets [PDF]

This paper presents an ordered search model in which consumers search both for price and product fitness. We show that there is price dispersion in equilibrium and prices rise in the order of search.
Zhou, Jidong
core   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Searchable encryption with randomized ciphertext and randomized keyword search

Journal of Mathematical Cryptology
Abstract The notion of public-key encryption with keyword search (PEKS) was introduced to search over encrypted data without performing any decryption. In this article, we propose a PEKS scheme in which both the encrypted keyword and the trapdoor are randomized so that the cloud server is not able to recognize ...
Calderini, Marco, Longo, Riccardo, Sala, Massimiliano, Villa, Irene   +3 more
openaire   +6 more sources

Triangular Index Ratio as an Alternative Method to the Alpha Angle for Defining the Presence of Cam Morphology: A Prospective Cohort Study

Arthritis Care &Research, EarlyView.
Objective Cam morphology, which is a significant risk factor for hip osteoarthritis, is commonly quantified by the alpha angle (AA). This study aims to explore the potential of the triangular index ratio (TIR) to quantify cam morphology on anteroposterior radiographs by assessing the association between TIR‐defined cam morphology and the development of
Jinchi Tang, Fleur Boel, Michiel M. A. van Buuren, Noortje S. Riedstra, Myrthe A. van den Berg, Jos Runhaar, Sita Bierma‐Zeinstra, Rintje Agricola   +7 more
wiley   +1 more source

Effects of Causal Beliefs About Gout on Public Views About Gout Management: A Randomized Experimental Study

Arthritis Care &Research, EarlyView.
Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch, Borislav Mihov, Anne Horne, Keith J. Petrie, Gregory D. Gamble, Lachlan Fleck, Nicola Dalbeth   +6 more
wiley   +1 more source

Optimal geometrical design of reshaping berm breakwaters based on minimizing administrative costs (Case Study: Farasakoo Breakwater) [PDF]

محیط زیست و مهندسی آب, 2016
So far, many studies have been done to design reshaping berm breakwaters (RBB) that mostly have provided the effect of individual parameter on structure stability. Accordingly, the presentation of systematic optimal geometrical design of RBB is necessary.
Mahmoud Mohammad Rezapour Tabari, Mohammad Navid Moghim   +1 more
doaj  

Towards a Theory of Randomized Search Heuristics [PDF]

, 2003
There is a well-developed theory about the algorithmic complexity of optimization problems. Complexity theory provides negative results which typically are based on assumptions like NP≠P or NP≠RP. Positive results are obtained by the design and analysis of clever algorithms. These algorithms are well-tuned for their specific domain.
openaire   +2 more sources

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source