Results 101 to 110 of about 4,448,600 (255)

Distribution Endpoint Estimation Assessment for the use in Metaheuristic Optimization Procedure

open access: yesMendel, 2018
Metaheuristic algorithms are often applied to numerous optimization problems, involving large-scale and mixed-integer instances, specifically. In this contribution we discuss some refinements from the extreme value theory to the lately proposed ...
Jan Holesovky
doaj   +1 more source

Hyperemia! Random Search

open access: yes, 2020
The rate of convergence of a multidimensional random search is found to improve xvhen the search region is restricted to a directed adaptive hypercone.
Associate Professor, M J Wozny   +1 more
core  

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

OAS-XGB: An OptiFlect Adaptive Search Optimization Framework Using XGBoost to Predict Length of Stay for CAD Patients

open access: yesIEEE Access
Accurately predicting the length of hospital stay for patients with coronary artery disease is important for effective healthcare resource management and enhancing patient outcomes.
Geetha Pratyusha Miriyala   +1 more
doaj   +1 more source

Random search algorithms

open access: yes, 2009
Random search algorithms are useful for many ill-structured global optimization problems with continuous and/or discrete variables. Typically random search algorithms sacrifice a guarantee of optimality for finding a good solution quickly with ...
Zelda B. Zabinsky
core  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Tuning Deep Learning for Predicting Aluminum Prices Under Different Sampling: Bayesian Optimization Versus Random Search

open access: yesEntropy
This work implements deep learning models to capture non-linear and complex data behavior in aluminum price data. Deep learning models include the long short-term memory (LSTM) and deep feedforward neural networks (FFNN).
Alicia Estefania Antonio Figueroa   +1 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

A Comparative Study of Hyperparameter Optimization for CatBoost: Random Search, Optuna, and Successive Halving

open access: yesJournal of Applied Informatics and Computing
This study aims to evaluate the effectiveness of three hyperparameter optimization approaches Random Search, Successive Halving, and Optuna in the CatBoost algorithm for modeling individual income using the 2024 SAKERNAS data.
Claudian Tikulimbong Tangdilomban   +2 more
doaj   +1 more source

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