Results 111 to 120 of about 12,241,994 (329)
Distribution Endpoint Estimation Assessment for the use in Metaheuristic Optimization Procedure
Mendel, 2018 Metaheuristic algorithms are often applied to numerous optimization problems, involving large-scale and mixed-integer instances, specifically. In this contribution we discuss some refinements from the extreme value theory to the lately proposed ...
Jan Holesovky
doaj +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Statistics of Global Stochastic Optimisation: How Many Steps to Hit the Target?
MathematicsRandom walks are considered in a one-dimensional monotonously decreasing energy landscape. To reach the minimum within a region Ωϵ, a number of downhill steps have to be performed.
Godehard Sutmann
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
IEEE AccessAccurately predicting the length of hospital stay for patients with coronary artery disease is important for effective healthcare resource management and enhancing patient outcomes.
Geetha Pratyusha Miriyala +1 more
doaj +1 more source
Erratum: OPRA-RS: A hearing-aid fitting method based on automatic speech recognition and random search. [PDF]
Front Neurosci, 2022 Frontiers Production Office.
europepmc +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Journal of Applied Informatics and ComputingThis study aims to evaluate the effectiveness of three hyperparameter optimization approaches Random Search, Successive Halving, and Optuna in the CatBoost algorithm for modeling individual income using the 2024 SAKERNAS data.
Claudian Tikulimbong Tangdilomban +2 more
doaj +1 more source
OPRA-RS: A Hearing-Aid Fitting Method Based on Automatic Speech Recognition and Random Search. [PDF]
Front Neurosci, 2022 Gonçalves Braz L +4 more
europepmc +1 more source