Results 101 to 110 of about 4,872,287 (279)
Journal of Applied Informatics and ComputingThis study aims to evaluate the effectiveness of three hyperparameter optimization approaches Random Search, Successive Halving, and Optuna in the CatBoost algorithm for modeling individual income using the 2024 SAKERNAS data.
Claudian Tikulimbong Tangdilomban +2 more
doaj +1 more source
OPRA-RS: A Hearing-Aid Fitting Method Based on Automatic Speech Recognition and Random Search. [PDF]
Front Neurosci, 2022 Gonçalves Braz L +4 more
europepmc +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
APPLICATION OF HYBRID RANDOM SEARCH METHOD TO OPTIMISATION OF ENGINEERING SYSTEMS’ PARAMETERS
Научный вестник МГТУ ГА, 2018 This paper presents a modification of the Luus-Jaakola global optimization method, which belongs to the class of metaheuristic algorithms. A hybrid method is suggested, using a combination of random search methods: Luus-Jaakola method, adaptive random ...
A. V. Panteleev, D. A. Rodionova
doaj +1 more source
Random Search as a Neural Network Optimization Strategy for Convolutional-Neural-Network (CNN)-based Noise Reduction in CT. [PDF]
Proc SPIE Int Soc Opt Eng, 2021 Huber NR +6 more
europepmc +1 more source
The Search for Constrained Random Generators
Proceedings of the ACM on Programming LanguagesAmong the biggest challenges in property-based testing (PBT) is the constrained random generation problem: given a predicate on program values, randomly sample from the set of all values, and only values, satisfying that predicate. Efficient solutions to this problem are critical, since the executable specifications used by PBT often ...
Harrison Goldstein +5 more
openaire +3 more sources
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Aging and Cancer, EarlyView.Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source