Results 101 to 110 of about 558,564 (263)

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son   +3 more
wiley   +1 more source

Random Resetting in Search Problems

open access: yes
Prepared as an invited chapter for the THE TARGET PROBLEM (Eds. D. S. Grebenkov, R. Metzler, G. Oshanin)
Pal, Arnab   +2 more
openaire   +2 more sources

Prevalence of Systemic Lupus Erythematosus in Australia, 2010–2022: A Population‐Based Study Using Linked National Administrative Health Data

open access: yesArthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...
Lucinda Roper   +7 more
wiley   +1 more source

Searchable encryption with randomized ciphertext and randomized keyword search

open access: yesJournal of Mathematical Cryptology
Abstract The notion of public-key encryption with keyword search (PEKS) was introduced to search over encrypted data without performing any decryption. In this article, we propose a PEKS scheme in which both the encrypted keyword and the trapdoor are randomized so that the cloud server is not able to recognize ...
Calderini, Marco   +3 more
openaire   +6 more sources

Optimal geometrical design of reshaping berm breakwaters based on minimizing administrative costs (Case Study: Farasakoo Breakwater) [PDF]

open access: yesمحیط زیست و مهندسی آب, 2016
So far, many studies have been done to design reshaping berm breakwaters (RBB) that mostly have provided the effect of individual parameter on structure stability. Accordingly, the presentation of systematic optimal geometrical design of RBB is necessary.
Mahmoud Mohammad Rezapour Tabari   +1 more
doaj  

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian   +4 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

Towards a Theory of Randomized Search Heuristics [PDF]

open access: yes, 2003
There is a well-developed theory about the algorithmic complexity of optimization problems. Complexity theory provides negative results which typically are based on assumptions like NP≠P or NP≠RP. Positive results are obtained by the design and analysis of clever algorithms. These algorithms are well-tuned for their specific domain.
openaire   +2 more sources

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy