Results 51 to 60 of about 561,945 (263)

Optimization Algorithm for Cutting Masonry with a Robotic Saw

Applied Sciences
The contribution of this study is in the novel application of the bin packing algorithm that is used to optimize the robotic bricklaying process with the aim of minimizing the wearing of a robotic saw used for splitting brick blocks so as to minimize ...
Vjačeslav Usmanov, Michal Kovářík, Rostislav Šulc, Čeněk Jarský   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Machine Learning-Based Energy Consumption and Carbon Footprint Forecasting in Urban Rail Transit Systems

Applied Sciences
In the fight against global climate change, the transportation sector is of critical importance because it is one of the major causes of total greenhouse gas emissions worldwide. Although urban rail transit systems offer a lower carbon footprint compared
Sertaç Savaş, Kamber Külahcı
doaj   +1 more source

Solving process planning and weighted scheduling with WNOPPT weighted due-date assignment problem using some pure and hybrid meta-heuristics

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2017
If we search literature for integrated process planning and scheduling problem and for scheduling with due date assignment problem we can find hundreds of researches made on these problems.
Halil İbrahim Demir, Caner Erden
doaj   +1 more source

Improving the Robustness and Quality of Biomedical CNN Models through Adaptive Hyperparameter Tuning

Applied Sciences, 2022
Deep learning is an obvious method for the detection of disease, analyzing medical images and many researchers have looked into it. However, the performance of deep learning algorithms is frequently influenced by hyperparameter selection, the question of
Saeed Iqbal, Adnan N. Qureshi, Amin Ullah, Jianqiang Li, Tariq Mahmood   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Comparison of N-BEATS with Standalone and Hybrid Deep Learning Models in Monthly Inflow Forecasting to the Aras Dam Reservoir: A Feature Selection Analysis

Journal of Agricultural Sciences
Reservoir dams play a pivotal role in water resource management. Accurate prediction of inflow to reservoirs significantly enhances operational performance.
Elman Athari, Mohammad Taghi Aalami, Mohammad Taghi Sattari   +2 more
doaj   +1 more source

Genetic Algorithms Applied to Optimize Neural Network Training in Reference Evapotranspiration Estimation [PDF]

Revista Brasileira de Meteorologia
The increased consumption of natural resources, such as water, has become a global concern. Consequently, determining information that can minimize water consumption, such as evapotranspiration, is increasingly necessary.
Eluã Ramos Coutinho, Jonni G.F. Madeira, Robson Mariano da Silva, Angel Ramon Sanchez Delgado, Alvaro L.G.A. Coutinho   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source