Results 61 to 70 of about 2,257,648 (287)

Genetic Algorithms Applied to Optimize Neural Network Training in Reference Evapotranspiration Estimation [PDF]

open access: yesRevista Brasileira de Meteorologia
The increased consumption of natural resources, such as water, has become a global concern. Consequently, determining information that can minimize water consumption, such as evapotranspiration, is increasingly necessary.
Eluã Ramos Coutinho   +4 more
doaj   +1 more source

Improving the Robustness and Quality of Biomedical CNN Models through Adaptive Hyperparameter Tuning

open access: yesApplied Sciences, 2022
Deep learning is an obvious method for the detection of disease, analyzing medical images and many researchers have looked into it. However, the performance of deep learning algorithms is frequently influenced by hyperparameter selection, the question of
Saeed Iqbal   +4 more
doaj   +1 more source

Optimal random search, fractional dynamics and fractional calculus

open access: yes, 2013
What is the most efficient search strategy for the random located target sites subject to the physical and biological constraints? Previous results suggested the L\'evy flight is the best option to characterize this optimal problem, however, which ...
Chen, YangQuan, Zeng, Caibin
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Developing a Multi-Region Stacking Ensemble Framework via Scenario-Based Digital Twin Simulation for Short-Term Household Energy Demand Forecasting

open access: yesApplied Sciences
Modern energy grids, with their regional diversity and complex consumption patterns, require accurate short-term forecasting for operational efficiency and reliability.
Akin Ozcift   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Modification of the random search method

open access: yesТехнічна інженерія, 2020
The paper considers linear programming problems with Boolean variables. This is a part of mathematical programming focused on solving practical optimization problems, which could be solved and correctly described with a mathematical model of the problem ...
S.I. Yaremchuk, O.A. Shupikov
doaj   +1 more source

Computer-aided diagnosis of lung nodule using gradient tree boosting and Bayesian optimization

open access: yes, 2017
We aimed to evaluate computer-aided diagnosis (CADx) system for lung nodule classification focusing on (i) usefulness of gradient tree boosting (XGBoost) and (ii) effectiveness of parameter optimization using Bayesian optimization (Tree Parzen Estimator,
Kojima, Ryosuke   +6 more
core   +2 more sources

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