Results 61 to 70 of about 609,661 (311)

Developing a Multi-Region Stacking Ensemble Framework via Scenario-Based Digital Twin Simulation for Short-Term Household Energy Demand Forecasting

open access: yesApplied Sciences
Modern energy grids, with their regional diversity and complex consumption patterns, require accurate short-term forecasting for operational efficiency and reliability.
Akin Ozcift   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Relational random forests based on random relational rules [PDF]

open access: yes, 2009
Random Forests have been shown to perform very well in propositional learning. FORF is an upgrade of Random Forests for relational data. In this paper we investigate shortcomings of FORF and propose an alternative algorithm, R⁴F, for generating Random ...
Pfahringer, Bernhard, Anderson, Grant
core  

Random Search Plus: A more effective random search for machine learning hyperparameters optimization [PDF]

open access: yes, 2020
Machine learning hyperparameter optimization has always been the key to improve model performance. There are many methods of hyperparameter optimization.
Li, Bohan
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Directed plateau search for MAX-k-SAT [PDF]

open access: yes, 2010
Local search algorithms for MAX-k-SAT must often explore large regions of mutually connected equal moves, or plateaus, typically by taking random walks through the region.
Howe, Adele   +5 more
core   +1 more source

Modification of the random search method

open access: yesТехнічна інженерія, 2020
The paper considers linear programming problems with Boolean variables. This is a part of mathematical programming focused on solving practical optimization problems, which could be solved and correctly described with a mathematical model of the problem ...
S.I. Yaremchuk, O.A. Shupikov
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Visual search in ecological and non-ecological displays: Evidence for a non-monotonic effect of complexity on performance [PDF]

open access: yes, 2012
Copyright @ 2013 PLoSThis article has been made available through the Brunel Open Access Publishing Fund.Considerable research has been carried out on visual search, with single or multiple targets. However, most studies have used artificial stimuli with
Philippe Chassy   +7 more
core   +1 more source

Optimization and Assessment of Wavelet Packet Decompositions with Evolutionary Computation

open access: yesEURASIP Journal on Advances in Signal Processing, 2003
In image compression, the wavelet transformation is a state-of-the-art component. Recently, wavelet packet decomposition has received quite an interest.
Schell Thomas, Uhl Andreas
doaj   +1 more source

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