Results 51 to 60 of about 3,736,992 (285)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

On potential kernels associated with random dynamical systems [PDF]

open access: yesOpuscula Mathematica, 2015
Let \((\theta,\varphi)\) be a continuous random dynamical system defined on a probability space \((\Omega,\mathcal{F},\mathbb{P})\) and taking values on a locally compact Hausdorff space \(E\).
Mohamed Hmissi   +2 more
doaj   +1 more source

Random-Matrix Ensembles for Semi-Separable Systems

open access: yes, 2001
Many models for chaotic systems consist of joining two integrable systems with incompatible constants of motion. The quantum counterparts of such models have a propagator which factorizes into two integrable parts. Each part can be diagonalized.
Prosen, Tomaz   +2 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Quenched free energy in random matrix model

open access: yesJournal of High Energy Physics, 2020
We compute the quenched free energy in the Gaussian random matrix model by directly evaluating the matrix integral without using the replica trick.
Kazumi Okuyama
doaj   +1 more source

Exact solutions to chaotic and stochastic systems

open access: yes, 2001
We investigate functions that are exact solutions to chaotic dynamical systems. A generalization of these functions can produce truly random numbers. For the first time, we present solutions to random maps.
Anishchenko   +54 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Non-Stationary Random Response of MDOF Duffing Systems

open access: yesShock and Vibration, 2004
This paper presents a method to solve non-stationary random responses of nonlinear multi-degrees-of-freedom (MDOF) Duffing systems subjected to evolutionary random excitations.
J.H. Lin, J. Wang, Y.H. Zhang
doaj   +1 more source

Criticality and entanglement in random quantum systems

open access: yes, 2009
We review studies of entanglement entropy in systems with quenched randomness, concentrating on universal behavior at strongly random quantum critical points.
Moore, Joel E., Refael, Gil
core   +1 more source

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