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openaire +5 more sources
Integrated machine learning framework for phenolic derivatives: classification (toxicity) and regression (logP) models identify top drug‐like compounds. Random Forest outperformed for toxicity, while Linear Regression best predicted logP. A weighted scoring approach prioritized five safe, lipophilicity‐optimized candidates, supporting rational ...
Houria Nacer +7 more
wiley +1 more source
Parallelizing MCMC with Random Partition Trees [PDF]
Xiangyu Wang +3 more
openalex +1 more source
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo +6 more
wiley +1 more source
Networks of random trees as a model of neuronal connectivity. [PDF]
Ajazi F, Chavez-Demoulin V, Turova T.
europepmc +1 more source
Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu +14 more
wiley +1 more source
Characterization of Phenotypic Variability of Sudanese Gum Arabic Tree <i>Acacia Senegal</i> var. <i>senegal</i> Using Multiprimer Random Amplificatıon of Polymorphic DNA (RAPD) [PDF]
Saad Samah Mahgoub Hassan Mohammed
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NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang +18 more
wiley +1 more source
A Predictive Classification Method for Email Phishing Attacks u sing Random Forest and A R trees
Sanjitha M +3 more
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Predicted Mapping of Seabed Sediments Based on MBES Backscatter and Bathymetric Data: A Case Study in Joseph Bonaparte Gulf, Australia, Using Random Forest Decision Tree [PDF]
Wei Xu +3 more
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