Results 131 to 140 of about 3,327,271 (332)
Two laws of large numbers for sublinear expectations
, 2015 In this paper, we consider the sublinear expectation on bounded random vari- ables. With the notion of uncorrelatedness for random variables under the sublinear expectation, a weak law of large numbers is obtained.
Sun, Chuanfeng
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
The asymptotic distribution of the sum of a random number of random variables [PDF]
, 1948 Herbert Robbins
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Upper and lower bounds for sums of random variables. [PDF]
In this contribution, the upper bounds for sums of dependent random variables X1 + X2 + … + X n derived by using comonotonicity are sharpened for the case when there exists a random variable Z such that the distribution functions of the Xi, given Z = z ...
Dhaene, Jan, Goovaerts, Marc, Kaas, R
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Evaluating A Key Instrumental Variable Assumption Using Randomization\n Tests [PDF]
, 2019 Zach Branson, Luke Keele
openalex +1 more source
Process Variable Importance Analysis by Use of Random Forests in a Shapley Regression Framework [PDF]
, 2020 Chris Aldrich
openalex +1 more source