Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Statistics of the Sum of Double Random Variables and Their Applications in Performance Analysis and Optimization of Simultaneously Transmitting and Reflecting Reconfigurable Intelligent Surface-Assisted Non-Orthogonal Multi-Access Systems. [PDF]
Minh BV +5 more
europepmc +1 more source
Classical (Local and Contextual) Probability Model for Bohm-Bell Type Experiments: No-Signaling as Independence of Random Variables. [PDF]
Khrennikov A, Alodjants A.
europepmc +1 more source
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
On the strong convergence for weighted sums of negatively superadditive dependent random variables. [PDF]
Meng B, Wang D, Wu Q.
europepmc +1 more source
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
On the probability density function of the product of Rayleigh distributed random variables
In this paper we investigate the distribution of the product of Rayleigh distributed random variables. Considering the Mellin-Barnes inversion formula and using the saddle point approach we obtain an upper bound for the product distribution. The accuracy
Widanagamage, Anushka +2 more
core
Some mean convergence theorems for arrays of rowwise pairwise negative quadrant dependent random variables. [PDF]
Chandra TK, Li D, Rosalsky A.
europepmc +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Precise large deviations for widely orthant dependent random variables with different distributions. [PDF]
Gao M, Wang K, Chen L.
europepmc +1 more source

