Results 121 to 130 of about 124,658 (311)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Random-walk behavior along task-irrelevant dimensions.

, 2019
In A), B), C), we show that our learning model predicts that updating aim based on reinforcement feedback can lead to random-walk behaviour along task-irrelevant dimensions.
Susan K. Coltman (6421388), Heather R. McGregor (4285279), Joshua G. A. Cashaback (4285276), Dimitrios J. Palidis (3740281), Christopher K. Lao (6421385), Paul L. Gribble (90279)   +5 more
core   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Angular asymptotics for multi-dimensional non-homogeneous random walks with asymptotically zero drift

, 2009
We study the rst exit time from an arbitrary cone with apex at the origin by a non-homogeneous random walk (Markov chain) on Zd (d 2) with mean drift that is asymptotically zero.
MacPhee, Iain M., MacPhee, I.M., Menshikov, MV, Menshikov, Mikhail V., MacPhee, IM, Wade, AR, Wade, Andrew R., Wade, A.R.   +7 more
core  

Limiting behaviour of random spatial graphs and asymptotically homogeneous RWRE [PDF]

, 2005
We consider several random spatial graphs of the nearest-neighbour type, including the k- nearest neighbours graph, the on-line nearest-neighbour graph, and the minimal directed spanning tree.
Wade, Andrew R, Andrew R. Wade,, Andrew R. Wade   +2 more
core  

rougier/random-walk: Version 1.1

, 2017
Re-run, Repeat, Reproduce, Replicate, Re ...
Fabien C. Y. Benureau, Nicolas P. Rougier   +1 more
core   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

On an Effective Solution of the Optimal Stopping Problem for Random Walks [PDF]

We find a solution of the optimal stopping problem for the case when a reward function is an integer function of a random walk on an infinite time interval. It is shown that an optimal stopping time is a first crossing time through a level defined as the
Albert Shiryaev, Alexander Novikov
core  

Random Walks in Tennis

Missouri Journal of Mathematical Sciences, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source