Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Toward standardized personalized nutrition: a methodological scoping review and meta-analysis of randomized controlled trials in adults with overweight and obesity. [PDF]
Duc TQ +4 more
europepmc +1 more source
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei +9 more
wiley +1 more source
A proposed reinforcement learning approach via discrete control reformulation and multi-step double DQN for adaptive cruise control in electric vehicles. [PDF]
Meghawer A +3 more
europepmc +1 more source
An innovative, lightweight 3D‐printed skinfold chamber system is presented for long‐term intravital imaging. This affordable, biocompatible platform simplifies surgical implantation and allows high‐resolution, multimodal visualization of the tumor microenvironment for up to four weeks.
Iván Cortés Domínguez +9 more
wiley +1 more source
Digital CBT reduces mental disorders and boosts access to care in college students. [PDF]
europepmc +1 more source
Step-Wise Dual Dynamic DPSGD: Enhancing Performance on Imbalanced Medical Datasets with Differential Privacy. [PDF]
Huang X, Xie F.
europepmc +1 more source
Stability of Medicinal Nanoemulsions to Spaceflight: Insights From the StarMed Experiment
Chitosan‐coated melatonin nanoemulsions (MN) recovered from a sounding rocket mission preserve droplet size and controlled‐release behavior, whereas uncoated nanoemulsions show ageing‐driven droplet growth and increased accessible drug fraction. Simple polymer coatings thus enhance the flight resilience of liquid space medicines under cumulative launch
Modupe Adebowale +4 more
wiley +1 more source
Management of Visual Loss Following Hyaluronic Acid Filler Injections: An Algorithm-based Approach. [PDF]
Snozzi P +4 more
europepmc +1 more source
A microfluidic device with magnetic microposts was used to assess platelet mechanobiology. The oscillatory actuation of posts with embedded iron particles was dampened by the dynamic stiffening of the platelet‐rich plugs. This stiffening process increased with applied load, but inhibiting platelet activation (ASA) or myosin contractility (blebbistatin)
Nikita Taparia +4 more
wiley +1 more source

