Results 61 to 70 of about 114,115 (267)
An introduction to randomized algorithms
The concept of randomization is known to be an extremely important tool for the design of algorithms. Its use often yields better time or space complexity compared with the best deterministic algorithms we know of for the same problem; moreover resulting randomized algorithms are often very simple to understand and implement.
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A randomized maximum-flow algorithm [PDF]
Summary: A randomized algorithm for computing a maximum flow is presented. For an \(n\)-vertex \(m\)-edge network, the running time is \(O(nm + n^2 (\log n)^2)\) with probability at least \(1 - 2^{- \sqrt {nm}}\). The algorithm is always correct, and in the worst case runs in \(O(nm \log n)\) time.
Cheriyan, J., Hagerup, T.
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EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
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A Monad for Randomized Algorithms
AbstractIn this paper, we introduce a monad of random choice for domains that does not suffer from the main two drawbacks of the probabilistic powerdomain. It is not known whether any Cartesian closed category of domains is closed under the probabilistic powerdomain, but the Cartesian closed category BCD is closed under this monad of random choice ...
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The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
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An accelerated randomized Kaczmarz algorithm [PDF]
The randomized Kaczmarz ( R K \rm {RK} )
Ji Liu 0002, Stephen J. Wright 0001
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On the Use of Biased-Randomized Algorithms for Solving Non-Smooth Optimization Problems
Soft constraints are quite common in real-life applications. For example, in freight transportation, the fleet size can be enlarged by outsourcing part of the distribution service and some deliveries to customers can be postponed as well; in inventory ...
Angel Alejandro Juan +4 more
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Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
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Do Randomized Algorithms Improve the Efficiency of Minimal Learning Machine?
Minimal Learning Machine (MLM) is a recently popularized supervised learning method, which is composed of distance-regression and multilateration steps. The computational complexity of MLM is dominated by the solution of an ordinary least-squares problem.
Joakim Linja +3 more
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