Results 61 to 70 of about 114,130 (267)
A randomized maximum-flow algorithm [PDF]
30th Annual Symposium on Foundations of Computer Science, 1989 Summary: A randomized algorithm for computing a maximum flow is presented. For an \(n\)-vertex \(m\)-edge network, the running time is \(O(nm + n^2 (\log n)^2)\) with probability at least \(1 - 2^{- \sqrt {nm}}\). The algorithm is always correct, and in the worst case runs in \(O(nm \log n)\) time.
Cheriyan, J., Hagerup, T.
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Randomized Parameterized Algorithms for the Kidney Exchange Problem
Algorithms, 2019 In order to increase the potential kidney transplants between patients and their incompatible donors, kidney exchange programs have been created in many countries.
Mugang Lin +3 more
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A Monad for Randomized Algorithms
Electronic Notes in Theoretical Computer Science, 2016 AbstractIn this paper, we introduce a monad of random choice for domains that does not suffer from the main two drawbacks of the probabilistic powerdomain. It is not known whether any Cartesian closed category of domains is closed under the probabilistic powerdomain, but the Cartesian closed category BCD is closed under this monad of random choice ...
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
An accelerated randomized Kaczmarz algorithm [PDF]
Mathematics of Computation, 2015 The randomized Kaczmarz ( R K \rm {RK} )
Ji Liu 0002, Stephen J. Wright 0001
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
On the Use of Biased-Randomized Algorithms for Solving Non-Smooth Optimization Problems
Algorithms, 2019 Soft constraints are quite common in real-life applications. For example, in freight transportation, the fleet size can be enlarged by outsourcing part of the distribution service and some deliveries to customers can be postponed as well; in inventory ...
Angel Alejandro Juan +4 more
doaj +1 more source