Results 91 to 100 of about 2,824,860 (307)

Algorithms with greedy heuristic procedures for mixture probability distribution separation [PDF]

open access: yesYugoslav Journal of Operations Research, 2019
For clustering problems based on the model of mixture probability distribution separation, we propose new Variable Neighbourhood Search algorithms (VNS) and evolutionary genetic algorithms (GA) with greedy agglomerative heuristic procedures and compare ...
Kazakovtsev Lev   +3 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Design of competitive paging algorithms with good behaviour in practice [PDF]

open access: yes, 2013
Paging is one of the most prominent problems in the field of online algorithms. We have to serve a sequence of page requests using a cache that can hold up to k pages. If the currently requested page is in cache we have a cache hit, otherwise we say that
Negoescu, Andrei Laurian
core  

Non-Algorithmic Theory of Randomness [PDF]

open access: yes, 2020
This paper proposes an alternative language for expressing results of the algorithmic theory of randomness. The language is more precise in that it does not involve unspecified additive or multiplicative constants, making mathematical results, in principle, applicable in practice.
openaire   +3 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Optimizing antibiotics in residents of nursing homes: protocol of a randomized trial

open access: yesBMC Health Services Research, 2002
Background Antibiotics are frequently prescribed for older adults who reside in long-term care facilities. A substantial proportion of antibiotic use in this setting is inappropriate.
Simor Andrew   +7 more
doaj   +1 more source

Quantum mechanics and algorithmic randomness [PDF]

open access: yesComplexity, 2000
plain LaTeX, 11 ...
openaire   +3 more sources

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

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