Results 91 to 100 of about 610,923 (291)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Effects of dietary aluminosilicate on growth performance, frequency of diarrhea, and blood profiles of weaned pigs

Journal of Animal Science and Technology
This study was designed with two experiments to investigate the effects of dietary aluminosilicate on growth performance, frequency of diarrhea, and blood profiles of weaned pigs. In Exp. 1, a total of 48 weaned pigs [initial body weight (BW) 7.65 ± 0.99
Jinuk Nam, Jong Nam Kim, Hyeun Bum Kim, Jin Ho Cho, Yonghee Kim, Jinmu Ahn, Yonggu Kang, Ikcheol Shin, Youngmin Park, Minho Song, Hyunjin Kyoung   +10 more
doaj   +1 more source

Investigation on the Grain Yield Stability of Promising Cold Region Bread Wheat Cultivars and Lines by Using Different Stability Statistics [PDF]

Ikufīziyuluzhī-i Giyāhān-i Zirā̒ī, 2015
This study was conducted to determine the yield stability of 10 cold region bread wheat genotypes, using a randomized complete block design with 3 replications for 4 years (2009-2013) at the Agricultural and Natural Resources Research Center of East ...
A. Tarinejad, M.S. Abedi
doaj  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Calibration of phosphorus fertilizer for barley (Hordeum vulgare L.) on cambisols of Endamekhoni, Northern Ethiopia

Cogent Food & Agriculture, 2019
Calibration of soil test P is a stage in determining P fertilizer rates to meet plant P requirement and soil nutrient availability. The objective of this study was to determine the critical phosphorous (Pc) and phosphorous requirement factor (Pf) for ...
Gidena Tasew Reda, Sofonyas Dargie, Birhane Hailu, Kidane Welde, Gebru Eyasu   +4 more
doaj   +1 more source

Effectiveness of paracervical block for pain relief in women undergoing hysterosalpingography

Journal of Human Reproductive Sciences, 2016
Objectives: To evaluate the potential benefit, in terms of pain relief, of the paracervical block with 2% lignocaine in women undergoing hysterosalpingography (HSG). Study Design: This study was a prospective randomized controlled study.
Shikha Jain, Dattaprasad B Inamdar, Abha Majumdar, Deepak K Jain   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Calidad de agropiro alargado (Thinopyrum ponticum) en estado vegetativo en relación con la edad y longitud de las hojas [PDF]

RIA: Revista Investigaciones Agropecuarias, 2013
The effect of leaf age and length on leaf blade quality was studied in wheatgrass leaf blades leaves (Thinopyrum ponticum cv. Hulk) from swards of two heights. Swards were grown in plots in a greenhouse (17± 4 ºC)in a randomized block design (n=3) of 160
DI MARCO, O.N., HARKES, H., AGNUSDEI, M.G   +2 more
doaj  

Did belowground N transfer in mixed plantations of Acacia mangium and Eucalyptus meet the Stress Gradient Hypothesis? [PDF]

, 2019
Belowground interactions in mixed forest plantations remain poorly understood as that of short-tenn nitrogen (N) transfer from N-fixing trees to non-N-fixing trees (Non-NFT) depending on nutrient availability. We investigated in this facilitation process
Amaral Guerrini, I., Bordron, Bruno, Bouillet, Jean-Pierre, De Oliveira, Ivanka Rosada, Gonçalves, José Leonardo M., Ribeiro Paula, Ranieri, Robin, Agnès, Vicente Ferraz, Alexandre   +7 more
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