Results 211 to 220 of about 188,812 (316)

Citation Velocity and Social Media Impact Analysis of Hip and Knee Arthroplasty Randomized Controlled Trials. [PDF]

Arthroplast Today
Temple JR, Barakat N, Carpenter LS, Novicoff WM, Browne JA.   +4 more
europepmc   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

The Scandinavian Displaced Lateral Clavicle trial (ScanDiLaC): a study protocol for a randomized clinical trial. [PDF]

Trials
Christersson P, Karimi D, Grønhaug K, Launonen A, Brorson S, Frihagen F, Viberg B, Hailer N, Wolf O.   +8 more
europepmc   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Randomized controlled trials – The what, when, how and why

Randomized controlled trials (RCTs) are at the top of the pyramid of evidence as they offer the best answer on the efficacy of a new treatment. RCTs are true experiments in which participants are randomly allocated to receive a certain intervention ...
Braga, Luis H., Haid, Bernhard, Ching, Christina, İrfan Dönmez, M., Bägli, Darius J., Kaefer, Martin, Harper, Luke, Kalfa, Nicholas, Herbst, Kathy, Cascio, Salvatore, Nieuwhof-Leppink, Anka, Fossum, Magdalena, Garriboli, Massimo, Farrokhyar, Forough, Nelson, Caleb P.   +14 more
core  

Comparison of Bracket Adhesion Failure Rates with Resin-Modified Glass Ionomer Cement Versus Conventional Resin Adhesives: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Dent J (Basel)
Sevindik CN, Barmak AB, Rossouw PE, Javed F.   +3 more
europepmc   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

Directly comparing randomized and real-world controls in adjuvant breast cancer. [PDF]

J Comp Eff Res
Walker B, Boyd M, Silver M, Shi J, Bulsara P, Balanchivadze N, Robert NJ.   +6 more
europepmc   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Editorial: Exploring exopolysaccharides: probiotic pathways from gut to brain health. [PDF]

Front Microbiol
D'Ambrosio S, Langa S, Cimini D.
europepmc   +1 more source