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Topical ketorolac as an adjunctive treatment with intravitreal bevacizumab in the management of diabetic macular edema: A double-masked placebo-controlled randomized clinical trial

Graefe's Archive for Clinical and Experimental Ophthalmology, 2021
To evaluate the additional effect of ketorolac eye drops on therapeutic effects of intravitreal Bevacizumab in patients with diabetic macular edema (DME) METHODS: In a randomized clinical trial, 50 patients with center involved DME (macular thickness ≥ 300 microns accompanied by decreased VA (24 
Homayoun Nikkhah   +6 more
openaire   +2 more sources

Mineralocorticoid Receptor Antagonists in Central Serous Chorioretinopathy: A Meta-Analysis of Randomized Controlled Trials.

Ophthalmology Retina, 2019
TOPIC A meta-analysis comparing mineralocorticoid receptor (MR) antagonists (eplerenone or spironolactone) versus observation or placebo in the treatment of central serous chorioretinopathy (CSCR) based on best-corrected visual acuity (BCVA) and ...
Sean K Wang   +4 more
semanticscholar   +1 more source

Efficacy and Safety of Topical Pidobenzone 4% as Adjuvant Treatment for Solar Lentigines: Result of a Randomized, Controlled, Clinical Trial

Dermatology, 2016
<b><i>Background/Objective:</i></b> This study aims at the evaluation of the efficacy and safety of a combination therapy based on pidobenzone 4% and fractional CO<sub>2</sub> laser or cryotherapy in the treatment of solar lentigines and the prevention of eventual posttreatment hyperchromia. <b><i>Methods:
Anna, Campanati   +9 more
openaire   +2 more sources

Comparison of Oral Voriconazole Versus Oral Ketoconazole as an Adjunct to Topical Natamycin in Severe Fungal Keratitis: A Randomized Controlled Trial

Cornea, 2017
Purpose: To compare the efficacy of oral voriconazole (VCZ) with oral ketoconazole (KCZ) as an adjunct to topical natamycin in severe fungal keratitis. Methods: Fifty eyes of 50 patients with proven severe fungal keratitis, (>5 mm size, involving >4 mm central cornea and > ...
Namrata, Sharma   +8 more
openaire   +2 more sources

2-Octyl Cyanoacrylate Topical Adhesive as an Alternative to Subcuticular Suture for Skin Closure After Total Knee Arthroplasty: A Randomized Controlled Trial in the Same Patient

The Journal of Arthroplasty, 2021
The 2-octyl cyanoacrylate topical adhesive with flexible self-adhesive polyester mesh (Dermabond Prineo) is becoming widely used in many surgical fields. However, no prior studies have tested the efficacy and safety of this topical adhesive compared with subcuticular suture in the same patient.
Keun Young Choi   +5 more
openaire   +2 more sources

Is topical antimycotic treatment useful as adjuvant therapy for flexural atopic dermatitis: randomized, double‐blind, controlled trial using one side of the elbow or knee as a control

International Journal of Dermatology, 2008
Abstract Background  Certain factors are known to cause exacerbation of atopic dermatitis (AD), e.g. soap, detergent, dry skin, staphylococcal colonization, and herpes infection. Other factors are suspected, but not yet proven, e.g. yeasts belonging to the Malassezia
Alson W K, Wong   +2 more
openaire   +2 more sources

Update on Randomized Placebo-Controlled Trials in the Past Decade for Treatment of Major Depressive Disorder in Child and Adolescent Patients: A Systematic Review

Journal of child and adolescent psychopharmacology, 2018
Objectives: Antidepressant treatment for major depressive disorder (MDD) has been a topic of continued interest with a number of placebo randomized-controlled trials (RCTs) being published in the past decade.
M. Ignaszewski, B. Waslick
semanticscholar   +1 more source

The role of the topical nasal decongestant oxymetazoline as a novel therapeutic option for post‐acne erythema: A split‐face, double‐blind, randomized, placebo‐controlled trial

The Journal of Dermatology, 2023
AbstractPost‐acne erythema (PAE) is one of the most common sequelae of acne inflammation. Unfortunately, the treatment of PAE remains challenging due to limited effective topical treatments. The objectives of this study were to evaluate the efficacy and safety of topical oxymetazoline hydrochloride (OxH) 0.05% solution for PAE.
Chanudda Washrawirul   +5 more
openaire   +2 more sources

Is Topical Vancomycin an Option? A Randomized Controlled Trial to Determine the Safety of the Topical Use of Vancomycin Powder in Preventing Postoperative Infections in Total Knee Arthroplasty, as Compared With Standard Postoperative Antibiotics

The Journal of Arthroplasty, 2023
The demand for total knee arthroplasties (TKAs) is expected to rise in the coming decades, increasing the burden of periprosthetic joint infections (PJIs). The use of intrawound vancomycin powder (VP) has proven to be effective in reducing the incidence of PJIs after spinal surgery. That said, its effectiveness in TKA remains unclear.
Wesam, Abuzaiter   +7 more
openaire   +2 more sources

Tranexamic acid for gastrointestinal bleeding: A systematic review with meta-analysis of randomized clinical trials.

American Journal of Emergency Medicine, 2020
BACKGROUND Acute gastrointestinal bleeding is a common life-threatening emergent condition. Immediate tranexamic acid is useful for reducing hemorrhage following operation and bleeding trauma, but evidence on the effects of tranexamic acid in patients ...
Po-Lin Lee   +5 more
semanticscholar   +1 more source

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