Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
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Optimal Test Design for Estimation of Mean Ability Growth. [PDF]
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Regulation of cell dynamics by rapid integrin transport through the biosynthetic pathway. [PDF]
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Gratitude interventions reduce cyber-aggression in adolescents: gender and disposition effects. [PDF]
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Cancer-associated fibroblast-derived circKLHL24 drives perineural invasion in pancreatic cancer via dual regulation of the sec31a-CXCL12 axis. [PDF]
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AI4CellFate: Interpretable Early Cell Fate Prediction with Generative AI
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