Results 91 to 100 of about 453,286 (286)
Detecting modules in dense weighted networks with the Potts method
, 2008 We address the problem of multiresolution module detection in dense weighted networks, where the modular structure is encoded in the weights rather than topology.
Arenas A +14 more
core +4 more sources
Tail behavior of randomly weighted sums with interdependent summands
We reconsider a classical, well-studied problem from applied probability. This is the max-sum equivalence of randomly weighted sums, and the originality is because we manage to include interdependence among the primary random variables, as well as among primary random variables and random weights, as a generalization of previously published results. As
Konstantinides, Dimitrios G. +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
A Competitive Genetic Algorithm for Single Row Facility Layout [PDF]
The single row facility layout is the NP-Hard problem of arranging facilities with given lengths on a line, so as to minimize the weighted sum of the distances between all pairs of facilities.
Ghosh, Diptesh, Kothari, Ravi
core
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Perturbed-History Exploration in Stochastic Linear Bandits
, 2019 We propose a new online algorithm for minimizing the cumulative regret in stochastic linear bandits. The key idea is to build a perturbed history, which mixes the history of observed rewards with a pseudo-history of randomly generated i.i.d.
Boutilier, Craig +3 more
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
An Exact Approach to Early/Tardy Scheduling with Release Dates [PDF]
In this paper we consider the single machine earliness/tardiness scheduling problem with di?erent release dates and no unforced idle time. The problem is decomposed into a weighted earliness subproblem and a weighted tardiness subproblem.
Jorge M. S. Valente, Rui A. F. S. Alves
core
Quantifying Triadic Closure in Multi-Edge Social Networks
, 2019 Multi-edge networks capture repeated interactions between individuals. In social networks, such edges often form closed triangles, or triads. Standard approaches to measure this triadic closure, however, fail for multi-edge networks, because they do not ...
Brandenberger, Laurence +3 more
core +1 more source