Results 231 to 240 of about 12,405,329 (295)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Spatial Variation of Key Bioclimatic Factors in the Natural Range of <i>Picea koraiensis</i> and Implications for Its Conservation. [PDF]

Biology (Basel)
Kaviriri DK, Liu T, Yang L.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Prehospital Transfusion With Red Blood Cells and Fresh Plasma in Helicopter Emergency Medical Services. [PDF]

Acta Anaesthesiol Scand
Andersen JB, Risgaard B, Schou R, Dahl M, Hansen TM, Johansson PI, Erikstrup C, Steinmetz J, Fenger-Eriksen C.   +8 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Silver-doped zinc oxide nanoparticles: synthesis, characterization and optimization of photocatalytic efficiencies in UV domains. [PDF]

RSC Adv
Arfaoui S, Mejri A, Eichendorff S, Mars A, Plantard G.   +4 more
europepmc   +1 more source

The Haematological and Biochemical Responses of Goat Bucks to Range Grazing and Indoor Concentrate-Based Feeding Systems. [PDF]

Vet Med Sci
Abraham S, Kechero Y, Wamatu J.
europepmc   +1 more source

Long-Range Hydrogen Gas Measurement via Raman and Rayleigh-Brillouin Backscattering. [PDF]

Sensors (Basel)
Park B, Sim J, Cho WB, Kim HS, Hwang IJ.
europepmc   +1 more source

In Vivo ³¹P-MRS of the Human Orthotopic Kidney at 3 Tesla. [PDF]

NMR Biomed
Carlsson E, Weis J, Svensson MK, Jafar M, Liss P, Sedigh A.   +5 more
europepmc   +1 more source

Transphyseal Separation of the Distal Humerus in a 5-Year-Old Child: A Rare Case Report. [PDF]

Case Rep Orthop
Pokhrel S, Karki S, Sah S, Tiwari G.
europepmc   +1 more source