Results 101 to 110 of about 55,786 (289)

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

Advanced Science, EarlyView.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao, Xinyu Wang, Zhifeng Wu, Xinya Zhang, Xiao Geng, Ti Zhang, Yue Wang, Hongwei Xia, Jun Zhang, Xianbo Qiu, Cuiru Sun, Yingjie Yu, Wenli Dai, Hua Tian, Qing Cai   +14 more
wiley   +1 more source

Análise da variação dos valores da rotação medial conforme a posição da diáfise do úmero Analysis on the variation of medial rotation values according to the position of the humeral diaphysis

Revista Brasileira de Ortopedia, 2012
OBJETIVO: Analisar a validade da medida de rotação medial (RM) do ombro pelos níveis vertebrais conforme a variação da posição da diáfise do úmero, testando o bigoniômetro como novo instrumental de aferição.
Alberto Naoki Miyazaki, Marcelo Fregoneze, Pedro Doneux Santos, Luciana Andrade da Silva, Guilherme do Val Sella, Carina Cohen, Taís Stedile Busin Giora, Sergio Luiz Checchia, Fabio Raia, Hélio Pekelman, Raquel Cymrot   +10 more
doaj   +1 more source

Mastication‐Induced Electrical Stimulation Activates Prg4+ Chondroprogenitors for Osteoarthritis Therapy

Advanced Science, EarlyView.
This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng, Jing‐Rong Cheng, Yu Qin, Jie Lei, Chen‐Chen Gao, Hong‐Ying Fu, Li‐Ping Wu, Thanh D. Nguyen, Xu‐Liang Deng, Kai‐Yuan Fu, Yang Liu   +10 more
wiley   +1 more source

Posterior chain flexibility and lower back pain in farm workers

Fisioterapia em Movimento
Introduction: Flexibility is an essential component of physical aptitude that reduces the incidence of muscle distention and improves movement efficiency and posture.
Marcia Regina da Silva, Lucimare Ferraz, Fátima Ferretti, Cristiane Sfredo   +3 more
doaj   +1 more source

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

Advanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang, Yingying Wang, Lujie Yu, Chunmei Jiang, Haoyu Liu, Yaohua Chen, Shutong Wu, Qin Liu, Lingling Wei, Xiaochun Zheng, Huifang Hao, Mengting Gao, Weiwei Kang, Rong Dai, Ziliang Zheng, Ruiping Zhang   +15 more
wiley   +1 more source

A Wireless 3D Magneto‐Mechanical Stimulation Platform Drives In Situ Chondrogenic Commitment of Endogenous MSCs

Advanced Science, EarlyView.
An intracellular magneto‐mechanical platform utilizing MSC‐targeted nanomotors is developed. After intra‐articular delivery, these nanomotors target endogenous BMSCs and are actuated within lysosomes to execute trans‐planar rotational‐bouncing motions under a rotating‐fluctuating 3D magnetic field, generating amplified mechanical stimulation.
Zhenguang Li, Li Peng, Laiya Lu, Yingying Wang, Xiaolei Chen, Feng Yin, Cuijun Deng, Yu Cheng   +7 more
wiley   +1 more source

Comparison of the efficacy of ultrasound-guided dextrose 25% hypertonic prolotherapy and intra-articular normal saline injection on pain, functional limitation, and range of motion in patients with knee osteoarthritis; a randomized controlled trial

BMC Musculoskeletal Disorders
Knee osteoarthritis (OA) is a debilitating condition that manifests as knee pain and dysfunction. Clinicians prefer non-surgical options such as intra-articular injections for mild to moderate disease. Dextrose prolotherapy (DPTx) has been shown to have a beneficial effect on knee OA in the long-term. In this randomized controlled trial (RCT), we aimed
Alireza Teymouri, Nafiseh Birang, Maryamsadat Fakheri, Aref Nasiri   +3 more
openaire   +3 more sources

The effect of pelvic tilt and cam on hip range of motion in young elite skiers and nonathletes

, 2018
Anna Swärd Aminoff,1 Cecilia Agnvall,2,3 Carl Todd,1 Páll Jónasson,4 Mikael Sansone,1 Olof Thoreson,1 Leif Swärd,1 Jon Karlsson,1 Adad Baranto1 1Department of Orthopaedics, Institute of Clinical Sciences at Sahlgrenska Academy ...
Thoreson O, Swärd L, Karlsson J, Jónasson P, Agnvall C, Baranto A, Swärd Aminoff A, Todd C, Sansone M   +8 more
core  

Continuous Passive Motion, Early Weight Bearing, And Active Motion Following Knee Articular Cartilage Repair: Evidence For Clinical Practice [PDF]

, 2010
Objective: To systematically review the literature regarding postoperative rehabilitation for articular cartilage repair: (1) Does the use of continuous passive motion (CPM) enhance healing, and if so, what parameters should be applied?
NC DOCKS at Appalachian State University, Howard, Jennifer   +1 more
core  

Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment

Advanced Science, EarlyView.
Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen, Jiaying Li, Jinjin Ma, Xiaonan Yuan, Yao Xiao, Yang Zhang, Yuan Chen, Hao Jiang, Hui He, Jie Hu, Qianglong Chen, Jinniu Zhang, Bin Li, Yun Zhou, Fengxuan Han, Yong Wang   +15 more
wiley   +1 more source