Results 121 to 130 of about 2,518,284 (281)

A randomized controlled trial with extended long-term follow-up: Quality of cervical spine motion after anterior cervical discectomy (ACD) or anterior cervical discectomy with arthroplasty (ACDA)

Brain and Spine
Introduction: In previous research, a consistent sequence of segmental contributions during dynamic extension X-rays of the cervical spine was observed in 80–90% of healthy participants.
Valérie N.E. Schuermans, Anouk Y.J.M. Smeets, Inez Curfs, Henk van Santbrink, Toon F.M. Boselie   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Reliability and Validity of the Single-Camera Markerless Motion Capture System for Measuring Shoulder Range of Motion in Healthy Individuals and Patients with Adhesive Capsulitis: A Single-Center Study

Sensors
Assessing shoulder joint range of motion (ROM) is essential for diagnosing musculoskeletal disorders and optimizing treatments. This single-center pilot study evaluated the reliability and validity of iBalance, a single-camera markerless motion capture ...
Suji Lee, Unhyung Lee, Yohwan Kim, Seungjin Noh, Hungu Lee, Seunghoon Lee   +5 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Combined Upper Cervical Mobilization and Shoulder Strengthening in Overhead Athletes with Cervical Hypermobility

Allied Medical Research Journal
Background: Throwing performance among athletes is significantly affected coupled with increased risk of injury in the presence of scapular dyskinesia. The condition is prevalent among 50% of athletes involving in overhead movements.
Shahnila Anum, Rabia Khan, Danish Latif   +2 more
doaj  

Flexibility of Knee Joint Muscles in Women with Knee Osteoarthritis and Healthy Controls

Journal of Rehabilitation Sciences and Research, 2015
Background: Osteoarthritis is one of the most common diseases in synovial joints. Due to high loading forces during weight-bearing activities, the knee joint is prone to degenerative processes.
Sara Abolahrari Shirazi, Farahnaz Ghafari Nezhad, Maryam Ebrahimian, Elham Nouraddini, Azadeh Mansoorian, Farahnaz Emami   +5 more
doaj  

Range of Motion [PDF]

, 2020
openaire   +1 more source