Results 71 to 80 of about 610,895 (263)

Education and Simulation of Range of Motion (ROM) for Caregivers to Improve the Quality of Life of Older People in the Community

Ahmar Metakarya
The aging process has caused various health problems, including limited physical mobility due to muscle weakness, joint stiffness, and certain chronic disease conditions. Efforts to maintain the health of older people can be done through Range of Motion (
I Gede Putu Darma Suyasa, Ni Kadek Sutini, Israfil Israfil, Ni Luh Dwi Indrayani, Ni Luh Putu Inca Buntari Agustini, I Nyoman Trisna Oka Putra Oka Putra   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Clinical and Radiographic Outcomes in Distal Radius Fractures Using K-wires versus Fragment-specific Plates: A Prospective Interventional Study

Journal of Clinical and Diagnostic Research
Introduction: Orthopaedic practice frequently deals with Distal Radius Fractures (DRFs); however, the treatment strategies for optimal functional outcomes remain uncertain.
Satyam Jawa, Vinod Nair
doaj   +1 more source

A motion aftereffect for long-range troboscopic apparent motion [PDF]

Perception & Psychophysics, 1986
The existence of a directional motion aftereffect (MAE) for long-range (LR) stroboscopic apparent motion (SAM) was examined with the use of a directionally ambiguous test stimulus. The spatial and temporal parameters were such that the LR, rather than the short-range, mechanism was likely to be implicated.
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Evaluation of the sagittal range of motion of the leg-foot after talocalcaneal arthrodesis

Journal of the Foot & Ankle
Introduction: Subtalar arthrosis is a disabling condition that can significantly impair hindfoot mechanics and overall foot function. Talocalcaneal arthrodesis is a well-established surgical procedure for pain relief and stabilization; however, its ...
Vitor Tavares Amaral Melo , Elisa Alves de Oliveira, Marcelo Marcucci Chakkour, Noé De Marchi Neto , Jordanna Maria Pereira Bergamasco, Marco Túlio Costa   +5 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source