Results 131 to 140 of about 2,160,574 (295)
Three Bosons in One Dimension with Short Range Interactions I: Zero Range Potentials
, 2005 We consider the three-boson problem with $\delta$-function interactions in one spatial dimension. Three different approaches are used to calculate the phase shifts, which we interpret in the context of the effective range expansion, for the scattering of
A. Amaya-Tapia +16 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Gyroscopes based on nitrogen-vacancy centers in diamond
, 2012 We propose solid-state gyroscopes based on ensembles of negatively charged nitrogen-vacancy (${\rm NV^-}$) centers in diamond. In one scheme, rotation of the nitrogen-vacancy symmetry axis will induce Berry phase shifts in the ${\rm NV^{-}}$ electronic ...
A. Jarmola +6 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
AnimalsWhile climate change and land-use change are known to interact in their effects on species’ range shifts, most studies have only focused on their isolated and combined effects, hindering a comprehensive understanding of their effects on future species ...
Xuzhe Zhao +5 more
doaj +1 more source
About the p-mode frequency shifts in HD 49933
, 2011 We study the frequency dependence of the frequency shifts of the low-degree p modes measured in the F5V star HD 49933, by analyzing the second run of observations collected by the CoRoT satellite.
Anguera Gubau +55 more
core +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source